Kim Bak Jensen
Professor
Jensen Lab
Blegdamsvej 3B, 2200 København N
Member of:
- Published
A Semi-automated Organoid Screening Method Demonstrates Epigenetic Control of Intestinal Epithelial Differentiation
Ostrop, J., Zwiggelaar, R. T., Terndrup Pedersen, M., Gerbe, F., Bösl, K., Lindholm, H. T., Díez-Sánchez, A., Parmar, N., Radetzki, S., von Kries, J. P., Jay, P., Jensen, Kim Bak, Arrowsmith, C. & Oudhoff, M. J., 2021, In: Frontiers in Cell and Developmental Biology. 8, p. 1-20 618552.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A bioengineering perspective on modelling the intestinal epithelial physiology in vitro
Antfolk, M. & Jensen, Kim Bak, 7 Dec 2020, In: Nature Communications. 11, 1, p. 1-11 6244.Research output: Contribution to journal › Review › Research › peer-review
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A biomechanical switch regulates the transition towards homeostasis in oesophageal epithelium
McGinn, J., Hallou, A., Han, S., Krizic, Kata, Ulyanchenko, Svetlana, Iglesias-Bartolome, R., England, F. J., Verstreken, C., Chalut, K. J., Jensen, Kim Bak, Simons, B. D. & Alcolea, M. P., May 2021, In: Nature Cell Biology. 23, 5, p. 511-525 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A genetically inducible porcine model of intestinal cancer
Callesen, M. M., Árnadóttir, S. S., Lyskjær, I., Ørntoft, M. B. W., Høyer, S., Dagnæs-Hansen, F., Liu, Y., Li, R., Callesen, H., Rasmussen, M. H., Berthelsen, M. F., Thomsen, M. K., Schweiger, P. J., Jensen, Kim Bak, Laurberg, S., Ørntoft, T. F., Elverløv-Jakobsen, J. E. & Andersen, C. L., Nov 2017, In: Molecular Oncology. 11, 11, p. 1616–1629 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
A stem cell gene expression profile of human squamous cell carcinomas
Jensen, Kim Bak, Jones, J. & Watt, F. M., 8 Dec 2008, In: Cancer Letters. 272, 1, p. 23-31 9 p.Research output: Contribution to journal › Journal article › Research
- Published
An organoid-based CRISPR-Cas9 screen for regulators of intestinal epithelial maturation and cell fate
Hansen, Stine Lind, Larsen, Hjalte List, Pikkupeura, Laura Maarit, Maciag, Grzegorz Jerzy, Guiu, J., Müller, I., Clement, Ditte Lynge, Mueller, C., Johansen, Jens Vilstrup, Helin, K., Lerdrup, Mads & Jensen, Kim Bak, 2023, In: Science Advances. 9, 28, 18 p., eadg4055.Research output: Contribution to journal › Journal article › Research › peer-review
Applying phage display technology in aging research
Kristensen, P., Ravn, P., Jensen, Kim Bak & Jensen, K., 2000, In: Biogerontology. 1, 1, p. 67-78 12 p.Research output: Contribution to journal › Review › Research › peer-review
Assaying proliferation and differentiation capacity of stem cells using disaggregated adult mouse epidermis
Jensen, Kim Bak, Driskell, R. R. & Watt, F. M., May 2010, In: Nature Protocols (Online). 5, 5, p. 898-911 14 p.Research output: Contribution to journal › Journal article › Research
- Published
Bimodal skin progenitors-a matter of place and time
Ulyanchenko, Svetlana & Jensen, Kim Bak, 15 Dec 2016, In: E M B O Journal. 35, 24, p. 2628-2630Research output: Contribution to journal › Letter › Research
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Biological techniques: An embryonic view of tumour development
Schweiger, P. J. & Jensen, Kim Bak, 12 Sep 2013, In: Nature. 501, 7466, p. 171-2 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
COX-2-PGE2 Signaling Impairs Intestinal Epithelial Regeneration and Associates with TNF Inhibitor Responsiveness in Ulcerative Colitis
Li, Yuan, Soendergaard, C., Bergenheim, F. H., Aronoff, D. M., Milne, G., Riis, Lene Buhl, Seidelin, Jakob Benedict, Jensen, Kim Bak & Nielsen, Ole Haagen, 2018, In: EBioMedicine. 36, p. 497-507Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cell biology: Unconventional translation in cancer
Pedersen, M. T. & Jensen, Kim Bak, 11 Jan 2017, In: Nature. 541, 7638, p. 471-472 2 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies
Boyd, M., Thodberg, M., Vitezic, M., Lange, J. B., Vitting-Seerup, K., Chen, Y., Coskun, M., Li, Y., Lo, B. Z. S., Klausen, P., Schweiger, P., Pedersen, A. G., Rapin, N. P. J-P., Skovgaard, K., Dahlgaard, K., Andersson, R., Terkelsen, T. B., Lilje, B., Troelsen, J. T., Petersen, A. M. & 7 others, , 2018, In: Nature Communications. 9, 19 p., 1661.Research output: Contribution to journal › Journal article › Research › peer-review
De novo identification of cell-type specific antibody-antigen pairs by phage display subtraction. Isolation of a human single chain antibody fragment against human keratin 14
Stausbøl-Grøn, B., Jensen, Kim Bak, Jensen, K. H., Jensen , M. Ø. & Clark, B. F., May 2001, In: European Journal of Biochemistry. 268, 10, p. 3099-107 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Detecting host responses to microbial stimulation using primary epithelial organoids
Lange, Jette Bornholdt, Müller, C. V., Nielsen, M. J., Strickertsson, J., Rago, D., Chen, Y., Maciag, Grzegorz Jerzy, Skov, Jonathan, Wellejus, A., Schweiger, P. J., Hansen, Stine Lind, Broholm, C., Gögenur, Ismail, Maimets, Martti, Sloth, S., Hendel, J., Baker, A., Sandelin, Albin Gustav & Jensen, Kim Bak, 2023, In: Gut Microbes. 15, 2, 16 p., 2281012.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Deucravacitinib (Sotyktu™) for plaque psoriasis
Granau, Agnete Marie, Boye, T. L., Jensen, Kim Bak & Nielsen, Ole Haagen, 2023, In: Trends in Pharmacological Sciences. 44, 4, p. 252-253Research output: Contribution to journal › Letter › Research › peer-review
- Published
Dietary Control of Skin Lipid Composition and Microbiome
Moestrup, K. S., Chen, Y., Schepeler, T., Schweiger, P. J. & Jensen, Kim Bak, 2018, In: The Journal of Investigative Dermatology. 138, 5, p. 1225-1228 4 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
Differential sensitivity of epidermal cell subpopulations to beta-catenin-induced ectopic hair follicle formation
Baker, C. M., Verstuyf, A., Jensen, Kim Bak & Watt, F. M., 1 Jul 2010, In: Developmental Biology. 343, 1-2, p. 40-50 11 p.Research output: Contribution to journal › Journal article › Research
Enhancement of DNA vaccine potency through linkage of antigen to filamentous bacteriophage coat protein III domain I
Cuesta, A. M., Suárez, E., Larsen, M., Jensen, Kim Bak, Sanz, L., Compte, M., Kristensen, P. & Alvarez-Vallina, L., Apr 2006, In: Immunology. 117, 4, p. 502-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
Environmental stimuli and intestinal stem cell behavior
Wong, V. W. Y. & Jensen, Kim Bak, 1 Aug 2012, In: Cell Cycle. 11, 15, p. 2767-8 2 p.Research output: Contribution to journal › Journal article › Research
Epidermal stem cell diversity and quiescence
Watt, F. M. & Jensen, Kim Bak, Aug 2009, In: E M B O Molecular Medicine (Online). 1, 5, p. 260-7 8 p.Research output: Contribution to journal › Journal article › Research
Epsilon haemoglobin specific antibodies with applications in noninvasive prenatal diagnosis
Sørensen, M. D., Gonzalez Dosal, R., Jensen, Kim Bak, Christensen, B., Kølvraa, S. & Jensen, U. B., 2009, In: Journal of Biomedicine and Biotechnology. 2009, p. 659219Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Extracellular matrix interactions provide tumor cells with an escape mechanism for commitment to differentiation
Schweiger, P. J., Le Bouteiller, M., Yui, S., Thodberg, Malte, Clement, Ditte Lynge & Jensen, Kim Bak, 2022, In: Gastroenterology. 163, 6, p. 1688-1690.e3 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fluorescence-based tracing of transplanted intestinal epithelial cells using confocal laser endomicroscopy
Bergenheim, F., Seidelin, Jakob Benedict, Pedersen, M. T., Mead, B. E., Jensen, Kim Bak, Karp, J. M. & Nielsen, Ole Haagen, 2019, In: Stem Cell Research & Therapy. 10, 1, p. 1-12 12 p., 148.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
From Definitive Endoderm to Gut-a Process of Growth and Maturation
Guiu, J. & Jensen, Kim Bak, 1 Sep 2015, In: Stem Cells and Development. 24, 17, p. 1972-83 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Functional improvement of antibody fragments using a novel phage coat protein III fusion system
Jensen, Kim Bak, Larsen, M., Pedersen, J. S., Christensen, P. A., Alvarez-Vallina, L., Goletz, S., Clark, B. F. C. & Kristensen, P., 8 Nov 2002, In: Molecular Cell Biology Research Communications. 298, 4, p. 566-73 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Functionally fused antibodies--a novel adjuvant fusion system
Larsen, M., Jensen, Kim Bak, Christensen, P. A., Suarez, E., Paris, D., Sanz, L., Ravn, P., Sauce, D., Saas, P., Goletz, S., Alvarez-Vallina, L. & Kristensen, P., 31 Dec 2008, In: Journal of Immunological Methods. 339, 2, p. 220-7 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Generation of multipotent foregut stem cells from human pluripotent stem cells
Hannan, N. R. F., Fordham, R. P., Syed, Y. A., Moignard, V., Berry, A., Bautista, R., Hanley, N. A., Jensen, Kim Bak & Vallier, L., 2013, In: Stem Cell Reviews. 1, 4, p. 293-306 14 p.Research output: Contribution to journal › Journal article › Research
- Published
Heterogeneity and plasticity of epidermal stem cells
Schepeler, T., Page, M. E. & Jensen, Kim Bak, Jul 2014, In: Development (Cambridge, England). 141, 13, p. 2559-2567 9 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Hippo signalling directs intestinal fate
le Bouteiller, M. C. M. & Jensen, Kim Bak, Jan 2015, In: Nature Cell Biology. 17, 1, p. 5-6 2 p.Research output: Contribution to journal › Journal article › Research
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IL-17R–EGFR axis links wound healing to tumorigenesis in Lrig1 + stem cells
Chen, X., Cai, G., Liu, C., Zhao, J., Gu, C., Wu, L., Hamilton, T. A., Zhang, C. J., Ko, J., Zhu, L., Qin, J., Vidimos, A., Koyfman, S., Gastman, B. R., Jensen, Kim Bak & Li, X., 1 Jan 2019, In: Journal of Experimental Medicine. 216, 1, p. 195-214 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ISSCR standards for the use of human stem cells in basic research
Ludwig, T. E., Andrews, P. W., Barbaric, I., Benvenisty, N., Bhattacharyya, A., Crook, J. M., Daheron, L. M., Draper, J. S., Healy, L. E., Huch, M., Inamdar, M. S., Jensen, K. B., Kurtz, A., Lancaster, M. A., Liberali, P., Lutolf, M. P., Mummery, C. L., Pera, M. F., Sato, Y., Shimasaki, N. & 7 others, , 2023, In: Stem Cell Reports. 18, 9, p. 1744-1752 9 p.Research output: Contribution to journal › Review › Research › peer-review
Identification of keratinocyte-specific markers using phage display and mass spectrometry
Jensen, Kim Bak, Jensen, O. N., Ravn, P., Clark, B. F. C. & Kristensen, P., Feb 2003, In: Molecular and Cellular Proteomics. 2, 2, p. 61-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Identification of phage antibodies toward the Werner protein by selection on Western blots
Ravn, P., Kjaer, S., Jensen, K. H., Wind, T., Jensen, Kim Bak, Kristensen, P., Brosh, R. M., Orren, D. K., Bohr, V. A. & Clark, B. F., Feb 2000, In: Electrophoresis. 21, 3, p. 509-16 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immune cell-derived signals governing epithelial phenotypes in homeostasis and inflammation
Hausmann, Annika, Steenholdt, Casper, Nielsen, Ole Haagen & Jensen, Kim Bak, 20 Mar 2024, In: Trends in Molecular Medicine. 30, 3, p. 239-251Research output: Contribution to journal › Review › Research › peer-review
- Published
In vivo studies should take priority when defining mechanisms of intestinal crypt morphogenesis
Guiu, J. & Jensen, Kim Bak, 2022, In: Cellular and Molecular Gastroenterology and Hepatology. 13, 1, 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Inhibiting RHOA Signaling in Mice Increases Glucose Tolerance and Numbers of Enteroendocrine and Other Secretory Cells in the Intestine
Petersen, N., Frimurer, Thomas Michael, Pedersen, M. T., Egerod, Kristoffer Lihme, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Grapin-Botton, A., Jensen, Kim Bak & Schwartz, Thue W., 2018, In: Gastroenterology. 155, 4, p. 1164-1176 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intestinal Organoids: A Tool for Modelling Diet–Microbiome–Host Interactions
Rubert, J., Schweiger, P. J., Mattivi, F., Tuohy, K., Jensen, Kim Bak & Lunardi, A., 2020, In: Trends in Endocrinology and Metabolism. 31, 11, p. 848-858Research output: Contribution to journal › Review › Research › peer-review
- Published
Intestinal barrier integrity and inflammatory bowel disease: Stem cell-based approaches to regenerate the barrier
Holmberg, F. E. O., Pedersen, J., Jørgensen, P., Soendergaard, C., Jensen, Kim Bak & Nielsen, Ole Haagen, Apr 2018, In: Journal of Tissue Engineering and Regenerative Medicine. 12, 4Research output: Contribution to journal › Review › Research › peer-review
- Published
Isolation and In Vitro Characterization of Epidermal Stem Cells
Moestrup, K. S., Andersen, M. S. & Jensen, Kim Bak, 2017, Adult Stem Cells: Methods in Molecular Biology. Paolo, D. N., Sinjiv, D. & Dinender K., S. (eds.). Humana Press, Vol. 1553. p. 67-83 17 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
Isolation of recombinant phage-displayed antibodies recognizing skin keratinocytes
Jensen, Kim Bak & Kristensen, P., 2005, In: Methods in molecular biology (Clifton, N.J.). 289, p. 359-70 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
LRIG1 regulates cadherin-dependent contact inhibition directing epithelial homeostasis and pre-invasive squamous cell carcinoma development
Lu, L., Teixeira, V. H., Yuan, Z., Graham, T. A., Endesfelder, D., Kolluri, K., Al-Juffali, N., Hamilton, N., Nicholson, A. G., Falzon, M., Kschischo, M., Swanton, C., Wright, N. A., Carroll, B., Watt, F. M., George, J. P., Jensen, Kim Bak, Giangreco, A. & Janes, S. M., Mar 2013, In: The Korean Journal of Pathology. 229, 4, p. 608-20 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
LSD1 represses a neonatal/reparative gene program in adult intestinal epithelium
Zwiggelaar, R. T., Lindholm, H. T., Fosslie, M., Terndrup Pedersen, M., Ohta, Y., Díez-sánchez, A., Martín-alonso, M., Ostrop, J., Matano, M., Parmar, N., Kvaløy, E., Spanjers, R. R., Nazmi, K., Rye, M., Drabløs, F., Arrowsmith, C., Arne Dahl, J., Jensen, Kim Bak, Sato, T. & Oudhoff, M. J., 2020, In: Science Advances. 6, 37, p. 1-15 eabc0367.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Loss of PACS-2 delays regeneration in DSS-induced colitis but does not affect the ApcMin model of colorectal cancer
Dombernowsky, S. L., Schwarz, J., Samsøe-Petersen, Jacob, Albrechtsen, Reidar, Jensen, Kim Bak, Thomas, G. & Kveiborg, Marie, 1 Jan 2017, In: OncoTarget. 8, 65, p. 108303-108315 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling
Wong, V. W. Y., Stange, D. E., Page, M. E., Buczacki, S., Wabik, A., Itami, S., van de Wetering, M., Poulsom, R., Wright, N. A., Trotter, M. W. B., Watt, F. M., Winton, D. J., Clevers, H. & Jensen, Kim Bak, Apr 2012, In: Nature Cell Biology. 14, 4, p. 401-8 8 p.Research output: Contribution to journal › Journal article › Research
Lrig1 expression defines a distinct multipotent stem cell population in mammalian epidermis
Jensen, Kim Bak, Collins, C. A., Nascimento, E., Tan, D. W., Frye, M., Itami, S. & Watt, F. M., 8 May 2009, In: Cell Stem Cell. 4, 5, p. 427-39 13 p.Research output: Contribution to journal › Journal article › Research
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Lrig1 expression identifies airway basal cells with high proliferative capacity and restricts lung squamous cell carcinoma growth
Succony, L., Gómez-López, S., Pennycuick, A., Alhendi, A. S. N., Davies, D., Clarke, S. E., Gowers, K. H. C., Wright, N. A., Jensen, Kim Bak & Janes, S. M., 2022, In: European Respiratory Journal. 59, 2000816.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lrig1 marks a population of gastric epithelial cells capable of long-term tissue maintenance and growth in vitro
Schweiger, P. J., Clement, Ditte Lynge, Page, M. E., Schepeler, T., Zou, X., Sirokmány, G., Watt, F. M. & Jensen, Kim Bak, 2018, In: Scientific Reports. 8, 11 p., 15255.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maintenance of high-turnover tissues during and beyond homeostasis
Banjac, Isidora, Maimets, Martti & Jensen, Kim Bak, 2023, In: Cell Stem Cell. 30, 4, p. 348-361 14 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Managing vitamin D deficiency in inflammatory bowel disease
Nielsen, Ole Haagen, Hansen, T. I., Gubatan, J. M., Jensen, Kim Bak & Rejnmark, L., 2019, In: Frontline Gastroenterology. 10, 4, p. 394-400 7 p., 31656565.Research output: Contribution to journal › Review › Research › peer-review
ID: 40090325
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Ret receptor tyrosine kinase sustains proliferation and tissue maturation in intestinal epithelia
Research output: Contribution to journal › Journal article › Research › peer-review
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368
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YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration
Research output: Contribution to journal › Journal article › Research › peer-review
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257
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Loss of PACS-2 delays regeneration in DSS-induced colitis but does not affect the ApcMin model of colorectal cancer
Research output: Contribution to journal › Journal article › Research › peer-review
Published