Kim Bak Jensen

Kim Bak Jensen

Professor

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    ORCID: 0000-0001-6569-1664

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    1. Published

      Hippo signalling directs intestinal fate

      le Bouteiller, M. C. M. & Jensen, Kim Bak, Jan 2015, In: Nature Cell Biology. 17, 1, p. 5-6 2 p.

      Research output: Contribution to journal › Journal article › Research

    2. Published

      LSD1 represses a neonatal/reparative gene program in adult intestinal epithelium

      Zwiggelaar, R. T., Lindholm, H. T., Fosslie, M., Terndrup Pedersen, M., Ohta, Y., Díez-sánchez, A., Martín-alonso, M., Ostrop, J., Matano, M., Parmar, N., Kvaløy, E., Spanjers, R. R., Nazmi, K., Rye, M., Drabløs, F., Arrowsmith, C., Arne Dahl, J., Jensen, Kim Bak, Sato, T. & Oudhoff, M. J., 2020, In: Science Advances. 6, 37, p. 1-15 eabc0367.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration

      Yui, S., Azzolin, L., Maimets, Martti, Pedersen, M. T., Fordham, R. P., Hansen, Stine Lind, Larsen, Hjalte List, Guiu, J., Alves, M. R. P., Friis, Carsten, Johansen, Jens Vilstrup, Li, Yuan, Madsen, C. D., Nakamura, T., Watanabe, M., Nielsen, Ole Haagen, Schweiger, P. J., Piccolo, S. & Jensen, Kim Bak, 1 Jan 2018, In: Cell Stem Cell. 22, 1, p. 35-49. e7 23 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Environmental stimuli and intestinal stem cell behavior

      Wong, V. W. Y. & Jensen, Kim Bak, 1 Aug 2012, In: Cell Cycle. 11, 15, p. 2767-8 2 p.

      Research output: Contribution to journal › Journal article › Research

    5. Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling

      Wong, V. W. Y., Stange, D. E., Page, M. E., Buczacki, S., Wabik, A., Itami, S., van de Wetering, M., Poulsom, R., Wright, N. A., Trotter, M. W. B., Watt, F. M., Winton, D. J., Clevers, H. & Jensen, Kim Bak, Apr 2012, In: Nature Cell Biology. 14, 4, p. 401-8 8 p.

      Research output: Contribution to journal › Journal article › Research

    6. Epidermal stem cell diversity and quiescence

      Watt, F. M. & Jensen, Kim Bak, Aug 2009, In: E M B O Molecular Medicine (Online). 1, 5, p. 260-7 8 p.

      Research output: Contribution to journal › Journal article › Research

    7. Published

      Transplantation of intestinal organoids into a mouse model of colitis

      Watanabe, S., Kobayashi, S., Ogasawara, N., Okamoto, R., Nakamura, T., Watanabe, M., Jensen, Kim Bak & Yui, S., 2022, In: Nature Protocols. 17, p. 649-671

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Bimodal skin progenitors-a matter of place and time

      Ulyanchenko, Svetlana & Jensen, Kim Bak, 15 Dec 2016, In: E M B O Journal. 35, 24, p. 2628-2630

      Research output: Contribution to journal › Letter › Research

    9. Single-cell gene expression profiling reveals functional heterogeneity of undifferentiated human epidermal cells

      Tan, D. W. M., Jensen, Kim Bak, Trotter, M. W. B., Connelly, J. T., Broad, S. & Watt, F. M., Apr 2013, In: Development. 140, 7, p. 1433-44 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Epsilon haemoglobin specific antibodies with applications in noninvasive prenatal diagnosis

      Sørensen, M. D., Gonzalez Dosal, R., Jensen, Kim Bak, Christensen, B., Kølvraa, S. & Jensen, U. B., 2009, In: Journal of Biomedicine and Biotechnology. 2009, p. 659219

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Lrig1 expression identifies airway basal cells with high proliferative capacity and restricts lung squamous cell carcinoma growth

      Succony, L., Gómez-López, S., Pennycuick, A., Alhendi, A. S. N., Davies, D., Clarke, S. E., Gowers, K. H. C., Wright, N. A., Jensen, Kim Bak & Janes, S. M., 2022, In: European Respiratory Journal. 59, 2000816.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. De novo identification of cell-type specific antibody-antigen pairs by phage display subtraction. Isolation of a human single chain antibody fragment against human keratin 14

      Stausbøl-Grøn, B., Jensen, Kim Bak, Jensen, K. H., Jensen , M. Ø. & Clark, B. F., May 2001, In: European Journal of Biochemistry. 268, 10, p. 3099-107 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Lrig1 marks a population of gastric epithelial cells capable of long-term tissue maintenance and growth in vitro

      Schweiger, P. J., Clement, Ditte Lynge, Page, M. E., Schepeler, T., Zou, X., Sirokmány, G., Watt, F. M. & Jensen, Kim Bak, 2018, In: Scientific Reports. 8, 11 p., 15255.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Biological techniques: An embryonic view of tumour development

      Schweiger, P. J. & Jensen, Kim Bak, 12 Sep 2013, In: Nature. 501, 7466, p. 171-2 2 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Extracellular matrix interactions provide tumor cells with an escape mechanism for commitment to differentiation

      Schweiger, P. J., Le Bouteiller, M., Yui, S., Thodberg, Malte, Clement, Ditte Lynge & Jensen, Kim Bak, 2022, In: Gastroenterology. 163, 6, p. 1688-1690.e3 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Modeling human disease using organotypic cultures

      Schweiger, P. J. & Jensen, Kim Bak, Dec 2016, In: Current Opinion in Cell Biology. 43, p. 22-29 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Heterogeneity and plasticity of epidermal stem cells

      Schepeler, T., Page, M. E. & Jensen, Kim Bak, Jul 2014, In: Development (Cambridge, England). 141, 13, p. 2559-2567 9 p.

      Research output: Contribution to journal › Review › Research › peer-review

    18. Published

      Reconstruction of the mouse extrahepatic biliary tree using primary human extrahepatic cholangiocyte organoids

      Sampaziotis, F., Justin, A. W., Tysoe, O. C., Sawiak, S., Godfrey, E. M., Upponi, S. S., Gieseck, R. L., de Brito, M. C., Berntsen, N. L., Gómez-Vázquez, M. J., Ortmann, D., Yiangou, L., Ross, A., Bargehr, J., Bertero, A., Zonneveld, M. C. F., Pedersen, M. T., Pawlowski, M., Valestrand, L., Madrigal, P. & 23 others, Georgakopoulos, N., Pirmadjid, N., Skeldon, G. M., Casey, J., Shu, W., Materek, P. M., Snijders, K. E., Brown, S. E., Rimland, C. A., Simonic, I., Davies, S. E., Jensen, Kim Bak, Zilbauer, M., Gelson, W. T. H., Alexander, G. J., Sinha, S., Hannan, N. R. F., Wynn, T. A., Karlsen, T. H., Melum, E., Markaki, A. E., Saeb-Parsy, K. & Vallier, L., Aug 2017, In: Nature Medicine. 23, 8, p. 954-963 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Intestinal Organoids: A Tool for Modelling Diet–Microbiome–Host Interactions

      Rubert, J., Schweiger, P. J., Mattivi, F., Tuohy, K., Jensen, Kim Bak & Lunardi, A., 2020, In: Trends in Endocrinology and Metabolism. 31, 11, p. 848-858

      Research output: Contribution to journal › Review › Research › peer-review

    20. Identification of phage antibodies toward the Werner protein by selection on Western blots

      Ravn, P., Kjaer, S., Jensen, K. H., Wind, T., Jensen, Kim Bak, Kristensen, P., Brosh, R. M., Orren, D. K., Bohr, V. A. & Clark, B. F., Feb 2000, In: Electrophoresis. 21, 3, p. 509-16 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Transcriptional and epigenomic profiling identifies YAP signaling as a key regulator of intestinal epithelium maturation

      Pikkupeura, Laura Maarit, Bardini Bressan, Raul, Guiu, J., Chen, Y., Maimets, Martti, Mayer, Daniela, Schweiger, P. J., Hansen, Stine Lind, Maciag, Grzegorz Jerzy, Larsen, Hjalte List, Lõhmussaar, Kadi, Pedersen, M. T., Teves, Joji Marie Yap, Lange, Jette Bornholdt, Benes, V., Sandelin, Albin Gustav & Jensen, Kim Bak, 2023, In: Science Advances. 9, 28, 16 p., eadf9460.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Inhibiting RHOA Signaling in Mice Increases Glucose Tolerance and Numbers of Enteroendocrine and Other Secretory Cells in the Intestine

      Petersen, N., Frimurer, Thomas Michael, Pedersen, M. T., Egerod, Kristoffer Lihme, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Grapin-Botton, A., Jensen, Kim Bak & Schwartz, Thue W., 2018, In: Gastroenterology. 155, 4, p. 1164-1176 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Ret receptor tyrosine kinase sustains proliferation and tissue maturation in intestinal epithelia

      Perea, D., Guiu, J., Hudry, B., Konstantinidou, C., Milona, A., Hadjieconomou, D., Carroll, T., Hoyer, N., Natarajan, D., Kallijärvi, J., Walker, J. A., Soba, P., Thapar, N., Burns, A. J., Jensen, Kim Bak & Miguel-Aliaga, I., 16 Oct 2017, In: EMBO Journal. 36, 20, p. 3029-3045 17 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Cell biology: Unconventional translation in cancer

      Pedersen, M. T. & Jensen, Kim Bak, 11 Jan 2017, In: Nature. 541, 7638, p. 471-472 2 p.

      Research output: Contribution to journal › Letter › Research › peer-review

    25. Published

      The epidermis comprises autonomous compartments maintained by distinct stem cell populations

      Page, M. E., Lombard, P., Ng, F., Göttgens, B. & Jensen, Kim Bak, 3 Oct 2013, In: Cell Stem Cell. 13, 4, p. 471-82 12 p.

      Research output: Contribution to journal › Journal article › Research

    26. Published

      A Semi-automated Organoid Screening Method Demonstrates Epigenetic Control of Intestinal Epithelial Differentiation

      Ostrop, J., Zwiggelaar, R. T., Terndrup Pedersen, M., Gerbe, F., Bösl, K., Lindholm, H. T., Díez-Sánchez, A., Parmar, N., Radetzki, S., von Kries, J. P., Jay, P., Jensen, Kim Bak, Arrowsmith, C. & Oudhoff, M. J., 2021, In: Frontiers in Cell and Developmental Biology. 8, p. 1-20 618552.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Managing vitamin D deficiency in inflammatory bowel disease

      Nielsen, Ole Haagen, Hansen, T. I., Gubatan, J. M., Jensen, Kim Bak & Rejnmark, L., 2019, In: Frontline Gastroenterology. 10, 4, p. 394-400 7 p., 31656565.

      Research output: Contribution to journal › Review › Research › peer-review

    28. Published

      Dietary Control of Skin Lipid Composition and Microbiome

      Moestrup, K. S., Chen, Y., Schepeler, T., Schweiger, P. J. & Jensen, Kim Bak, 2018, In: The Journal of Investigative Dermatology. 138, 5, p. 1225-1228 4 p.

      Research output: Contribution to journal › Comment/debate › Research › peer-review

    29. Published

      Isolation and In Vitro Characterization of Epidermal Stem Cells

      Moestrup, K. S., Andersen, M. S. & Jensen, Kim Bak, 2017, Adult Stem Cells: Methods in Molecular Biology. Paolo, D. N., Sinjiv, D. & Dinender K., S. (eds.). Humana Press, Vol. 1553. p. 67-83 17 p. (Methods in molecular biology (Clifton, N.J.)).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    30. Published

      A biomechanical switch regulates the transition towards homeostasis in oesophageal epithelium

      McGinn, J., Hallou, A., Han, S., Krizic, Kata, Ulyanchenko, Svetlana, Iglesias-Bartolome, R., England, F. J., Verstreken, C., Chalut, K. J., Jensen, Kim Bak, Simons, B. D. & Alcolea, M. P., May 2021, In: Nature Cell Biology. 23, 5, p. 511-525 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      Mesenchymal-epithelial crosstalk shapes intestinal regionalisation via Wnt and Shh signalling

      Maimets, Martti, Pedersen, M. T., Guiu, J., Dreier, J., Thodberg, Malte, Antoku, Yasuko, Schweiger, P. J., Rib, Leonor, Bardini Bressan, Raul, Miao, Y., Garcia, K. C., Sandelin, Albin Gustav, Serup, Palle & Jensen, Kim Bak, 2022, In: Nature Communications. 13, 12 p., 715.

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      ISSCR standards for the use of human stem cells in basic research

      Ludwig, T. E., Andrews, P. W., Barbaric, I., Benvenisty, N., Bhattacharyya, A., Crook, J. M., Daheron, L. M., Draper, J. S., Healy, L. E., Huch, M., Inamdar, M. S., Jensen, K. B., Kurtz, A., Lancaster, M. A., Liberali, P., Lutolf, M. P., Mummery, C. L., Pera, M. F., Sato, Y., Shimasaki, N. & 7 others, Smith, A. G., Song, J., Spits, C., Stacey, G., Wells, C. A., Zhao, T. & Mosher, J. T., 2023, In: Stem Cell Reports. 18, 9, p. 1744-1752 9 p.

      Research output: Contribution to journal › Review › Research › peer-review

    33. LRIG1 regulates cadherin-dependent contact inhibition directing epithelial homeostasis and pre-invasive squamous cell carcinoma development

      Lu, L., Teixeira, V. H., Yuan, Z., Graham, T. A., Endesfelder, D., Kolluri, K., Al-Juffali, N., Hamilton, N., Nicholson, A. G., Falzon, M., Kschischo, M., Swanton, C., Wright, N. A., Carroll, B., Watt, F. M., George, J. P., Jensen, Kim Bak, Giangreco, A. & Janes, S. M., Mar 2013, In: The Korean Journal of Pathology. 229, 4, p. 608-20 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. Published

      COX-2-PGE2 Signaling Impairs Intestinal Epithelial Regeneration and Associates with TNF Inhibitor Responsiveness in Ulcerative Colitis

      Li, Yuan, Soendergaard, C., Bergenheim, F. H., Aronoff, D. M., Milne, G., Riis, Lene Buhl, Seidelin, Jakob Benedict, Jensen, Kim Bak & Nielsen, Ole Haagen, 2018, In: EBioMedicine. 36, p. 497-507

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      Primary monocytes derived from ulcerative colitis show no difference in the TNF-alpha-induced immune response among responders and primary non-responders to infliximab

      Li, Y., Jensen, Kim Bak, Seidelin, Jakob Benedict & Nielsen, O. H., Sep 2017, In: Journal of Gastroenterology and Hepatology. 32, S3, p. 138-138 P-0750.

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    36. Functionally fused antibodies--a novel adjuvant fusion system

      Larsen, M., Jensen, Kim Bak, Christensen, P. A., Suarez, E., Paris, D., Sanz, L., Ravn, P., Sauce, D., Saas, P., Goletz, S., Alvarez-Vallina, L. & Kristensen, P., 31 Dec 2008, In: Journal of Immunological Methods. 339, 2, p. 220-7 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      Reprogramming cellular identity during intestinal regeneration

      Larsen, Hjalte List & Jensen, Kim Bak, 2021, In: Current Opinion in Genetics & Development. 70, p. 40-47 8 p.

      Research output: Contribution to journal › Review › Research › peer-review

    38. Applying phage display technology in aging research

      Kristensen, P., Ravn, P., Jensen, Kim Bak & Jensen, K., 2000, In: Biogerontology. 1, 1, p. 67-78 12 p.

      Research output: Contribution to journal › Review › Research › peer-review

    39. Published

      Mucosal vitamin D signaling in inflammatory bowel disease

      Kellermann, L., Jensen, Kim Bak, Bergenheim, F., Gubatan, J., Chou, N. D., Moss, A. & Nielsen, Ole Haagen, 2020, In: Autoimmunity Reviews. 19, 11, 102672.

      Research output: Contribution to journal › Review › Research › peer-review

    40. Functional improvement of antibody fragments using a novel phage coat protein III fusion system

      Jensen, Kim Bak, Larsen, M., Pedersen, J. S., Christensen, P. A., Alvarez-Vallina, L., Goletz, S., Clark, B. F. C. & Kristensen, P., 8 Nov 2002, In: Molecular Cell Biology Research Communications. 298, 4, p. 566-73 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Published

      Organoids are not organs: Sources of variation and misinformation in organoid biology

      Jensen, Kim Bak & Little, Melissa Helen, 2023, In: Stem Cell Reports. 18, 6, p. 1255-1270 16 p.

      Research output: Contribution to journal › Review › Research › peer-review

    42. Isolation of recombinant phage-displayed antibodies recognizing skin keratinocytes

      Jensen, Kim Bak & Kristensen, P., 2005, In: Methods in molecular biology (Clifton, N.J.). 289, p. 359-70 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Identification of keratinocyte-specific markers using phage display and mass spectrometry

      Jensen, Kim Bak, Jensen, O. N., Ravn, P., Clark, B. F. C. & Kristensen, P., Feb 2003, In: Molecular and Cellular Proteomics. 2, 2, p. 61-9 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. A stem cell gene expression profile of human squamous cell carcinomas

      Jensen, Kim Bak, Jones, J. & Watt, F. M., 8 Dec 2008, In: Cancer Letters. 272, 1, p. 23-31 9 p.

      Research output: Contribution to journal › Journal article › Research

    45. Single-cell expression profiling of human epidermal stem and transit-amplifying cells: Lrig1 is a regulator of stem cell quiescence

      Jensen, Kim Bak & Watt, F. M., 8 Aug 2006, In: Proceedings of the National Academy of Sciences of the United States of America. 103, 32, p. 11958-63 6 p.

      Research output: Contribution to journal › Journal article › Research

    46. Lrig1 expression defines a distinct multipotent stem cell population in mammalian epidermis

      Jensen, Kim Bak, Collins, C. A., Nascimento, E., Tan, D. W., Frye, M., Itami, S. & Watt, F. M., 8 May 2009, In: Cell Stem Cell. 4, 5, p. 427-39 13 p.

      Research output: Contribution to journal › Journal article › Research

    47. Assaying proliferation and differentiation capacity of stem cells using disaggregated adult mouse epidermis

      Jensen, Kim Bak, Driskell, R. R. & Watt, F. M., May 2010, In: Nature Protocols (Online). 5, 5, p. 898-911 14 p.

      Research output: Contribution to journal › Journal article › Research

    48. Rac1 deletion causes thymic atrophy

      Hunziker, L., Benitah, S. A., Aznar Benitah, S., Braun, K. M., Jensen, Kim Bak, McNulty, K., Butler, C., Potton, E., Nye, E., Boyd, R., Laurent, G., Glogauer, M., Wright, N. A., Watt, F. M. & Janes, S. M., 29 Apr 2011, In: PLOS ONE. 6, 4, p. e19292

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Published

      Intestinal barrier integrity and inflammatory bowel disease: Stem cell-based approaches to regenerate the barrier

      Holmberg, F. E. O., Pedersen, J., Jørgensen, P., Soendergaard, C., Jensen, Kim Bak & Nielsen, Ole Haagen, Apr 2018, In: Journal of Tissue Engineering and Regenerative Medicine. 12, 4

      Research output: Contribution to journal › Review › Research › peer-review

    50. Published

      Tuft Cells and Their Role in Intestinal Diseases

      Hendel, S. K., Kellermann, L., Hausmann, Annika, Bindslev, Niels, Jensen, Kim Bak & Nielsen, Ole Haagen, 2022, In: Frontiers in Immunology. 13, 13 p., 822867.

      Research output: Contribution to journal › Review › Research › peer-review

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