Kim Bak Jensen

Kim Bak Jensen

Professor

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    ORCID: 0000-0001-6569-1664

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    1. Published

      Stem cell heterogeneity revealed

      Andersen, M. S. & Jensen, Kim Bak, Jun 2016, In: Nature Cell Biology. 18, 6, p. 587-9 3 p.

      Research output: Contribution to journal › Letter › Research › peer-review

    2. Published

      Tracing the cellular dynamics of sebaceous gland development in normal and perturbed states

      Andersen, M. S., Hannezo, E., Ulyanchenko, Svetlana, Estrach, S., Antoku, Yasuko, Pisano, S., Boonekamp, K. E., Sendrup, S., Maimets, Martti, Pedersen, M. T., Johansen, Jens Vilstrup, Clement, Ditte Lynge, Feral, C. C., Simons, B. D. & Jensen, Kim Bak, 2019, In: Nature Cell Biology. 21, 8, p. 924-932

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      A bioengineering perspective on modelling the intestinal epithelial physiology in vitro

      Antfolk, M. & Jensen, Kim Bak, 7 Dec 2020, In: Nature Communications. 11, 1, p. 1-11 6244.

      Research output: Contribution to journal › Review › Research › peer-review

    4. Differential sensitivity of epidermal cell subpopulations to beta-catenin-induced ectopic hair follicle formation

      Baker, C. M., Verstuyf, A., Jensen, Kim Bak & Watt, F. M., 1 Jul 2010, In: Developmental Biology. 343, 1-2, p. 40-50 11 p.

      Research output: Contribution to journal › Journal article › Research

    5. Published

      Maintenance of high-turnover tissues during and beyond homeostasis

      Banjac, Isidora, Maimets, Martti & Jensen, Kim Bak, 2023, In: Cell Stem Cell. 30, 4, p. 348-361 14 p.

      Research output: Contribution to journal › Review › Research › peer-review

    6. Published

      Fluorescence-based tracing of transplanted intestinal epithelial cells using confocal laser endomicroscopy

      Bergenheim, F., Seidelin, Jakob Benedict, Pedersen, M. T., Mead, B. E., Jensen, Kim Bak, Karp, J. M. & Nielsen, Ole Haagen, 2019, In: Stem Cell Research & Therapy. 10, 1, p. 1-12 12 p., 148.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Personalized B cell response to the Lactobacillus rhamnosus GG probiotic in healthy human subjects: a randomized trial

      Lange, Jette Bornholdt, Chen, Y., Rago, Alfredo, Sloth, S., Hendel, J., Melsæther, C., Müller, C. V., Juul Nielsen, M., Strickertsson, J., Engelholm, Lars Henning, Vitting-Seerup, K., Jensen, Kim Bak, Baker, A. & Sandelin, Albin Gustav, 9 Nov 2020, In: Gut Microbes. 12, 1, p. 1-14 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Detecting host responses to microbial stimulation using primary epithelial organoids

      Lange, Jette Bornholdt, Müller, C. V., Nielsen, M. J., Strickertsson, J., Rago, D., Chen, Y., Maciag, Grzegorz Jerzy, Skov, Jonathan, Wellejus, A., Schweiger, P. J., Hansen, Stine Lind, Broholm, C., Gögenur, Ismail, Maimets, Martti, Sloth, S., Hendel, J., Baker, A., Sandelin, Albin Gustav & Jensen, Kim Bak, 2023, In: Gut Microbes. 15, 2, 16 p., 2281012.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies

      Boyd, M., Thodberg, M., Vitezic, M., Lange, J. B., Vitting-Seerup, K., Chen, Y., Coskun, M., Li, Y., Lo, B. Z. S., Klausen, P., Schweiger, P., Pedersen, A. G., Rapin, N. P. J-P., Skovgaard, K., Dahlgaard, K., Andersson, R., Terkelsen, T. B., Lilje, B., Troelsen, J. T., Petersen, A. M. & 7 others, Jensen, Kim Bak, Gögenur, Ismail, Thielsen, P., Seidelin, Jakob Benedict, Nielsen, Ole Haagen, Bjerrum, Jakob Tveiten & Sandelin, Albin Gustav, 2018, In: Nature Communications. 9, 19 p., 1661.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Molecular Manipulations and Intestinal Stem Cell-Derived Organoids in Inflammatory Bowel Disease

      Boye, T. L., Steenholdt, Casper, Jensen, Kim Bak & Nielsen, Ole Haagen, 2022, In: Stem Cells. 40, 5, p. 447-457

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      A genetically inducible porcine model of intestinal cancer

      Callesen, M. M., Árnadóttir, S. S., Lyskjær, I., Ørntoft, M. B. W., Høyer, S., Dagnæs-Hansen, F., Liu, Y., Li, R., Callesen, H., Rasmussen, M. H., Berthelsen, M. F., Thomsen, M. K., Schweiger, P. J., Jensen, Kim Bak, Laurberg, S., Ørntoft, T. F., Elverløv-Jakobsen, J. E. & Andersen, C. L., Nov 2017, In: Molecular Oncology. 11, 11, p. 1616–1629 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      IL-17R–EGFR axis links wound healing to tumorigenesis in Lrig1 + stem cells

      Chen, X., Cai, G., Liu, C., Zhao, J., Gu, C., Wu, L., Hamilton, T. A., Zhang, C. J., Ko, J., Zhu, L., Qin, J., Vidimos, A., Koyfman, S., Gastman, B. R., Jensen, Kim Bak & Li, X., 1 Jan 2019, In: Journal of Experimental Medicine. 216, 1, p. 195-214 20 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Tissue-Engineering the Intestine: The Trials before the Trials

      Clevers, H., Conder, R. K., Li, V. S. W., Lutolf, M. P., Vallier, L., Chan, S., Grikscheit, T. C., Jensen, Kim Bak & De Coppi, P., 6 Jun 2019, In: Cell Stem Cell. 24, 6, p. 855-859 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Polyclonal origin and hair induction ability of dermal papillae in neonatal and adult mouse back skin

      Collins, C. A., Jensen, Kim Bak, MacRae, E. J., Mansfield, W. & Watt, F. M., 15 Jun 2012, In: Developmental Biology. 366, 2, p. 290-7 8 p.

      Research output: Contribution to journal › Journal article › Research

    15. Enhancement of DNA vaccine potency through linkage of antigen to filamentous bacteriophage coat protein III domain I

      Cuesta, A. M., Suárez, E., Larsen, M., Jensen, Kim Bak, Sanz, L., Compte, M., Kristensen, P. & Alvarez-Vallina, L., Apr 2006, In: Immunology. 117, 4, p. 502-6 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Loss of PACS-2 delays regeneration in DSS-induced colitis but does not affect the ApcMin model of colorectal cancer

      Dombernowsky, S. L., Schwarz, J., Samsøe-Petersen, Jacob, Albrechtsen, Reidar, Jensen, Kim Bak, Thomas, G. & Kveiborg, Marie, 1 Jan 2017, In: OncoTarget. 8, 65, p. 108303-108315 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Sox2-positive dermal papilla cells specify hair follicle type in mammalian epidermis

      Driskell, R. R., Giangreco, A., Jensen, Kim Bak, Mulder, K. W. & Watt, F. M., Aug 2009, In: Development (Cambridge, England). 136, 16, p. 2815-23 9 p.

      Research output: Contribution to journal › Journal article › Research

    18. Reporting live from the epidermal stem cell compartment!

      Fordham, R. P. & Jensen, Kim Bak, 3 Aug 2012, In: Cell Stem Cell. 11, 2, p. 141-2 2 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Transplantation of Expanded Fetal Intestinal Progenitors Contributes to Colon Regeneration after Injury

      Fordham, R. P., Yui, S., Hannan, N. R. F., Soendergaard, C., Madgwick, A., Schweiger, P. J., Nielsen, Ole Haagen, Vallier, L., Pedersen, R. A., Nakamura, T., Watanabe, M. & Jensen, Kim Bak, 5 Dec 2013, In: Cell Stem Cell. 13, 6, p. 734-744 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Necl2 regulates epidermal adhesion and wound repair

      Giangreco, A., Jensen, Kim Bak, Takai, Y., Miyoshi, J. & Watt, F. M., Oct 2009, In: Development (Cambridge, England). 136, 20, p. 3505-14 10 p.

      Research output: Contribution to journal › Journal article › Research

    21. Published

      Deucravacitinib (Sotyktu™) for plaque psoriasis

      Granau, Agnete Marie, Boye, T. L., Jensen, Kim Bak & Nielsen, Ole Haagen, 2023, In: Trends in Pharmacological Sciences. 44, 4, p. 252-253

      Research output: Contribution to journal › Letter › Research › peer-review

    22. Published

      Tracing the origin of adult intestinal stem cells

      Guiu, J., Hannezo, E., Yui, S., Demharter, S., Ulyanchenko, Svetlana, Maimets, Martti, Jørgensen, A., Perlman, S., Lundvall, L., Mamsen, L. S., Larsen, A., Olesen, R. H., Andersen, C. Y., Thuesen, L. L., Hare, Kristine Juul, Pers, Tune H, Khodosevich, Konstantin, Simons, B. D. & Jensen, Kim Bak, 2019, In: Nature. 570, 7759, p. 107-111

      Research output: Contribution to journal › Letter › Research › peer-review

    23. Published

      From Definitive Endoderm to Gut-a Process of Growth and Maturation

      Guiu, J. & Jensen, Kim Bak, 1 Sep 2015, In: Stem Cells and Development. 24, 17, p. 1972-83 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Rebuttal to: Organoid vs Mouse Model: Which is a Better Research Tool to Understand the Biologic Mechanisms of Intestinal

      Guiu, J. & Jensen, Kim Bak, 2022, In: Cellular and Molecular Gastroenterology and Hepatology. 13, 1, p. 193 1 p.

      Research output: Contribution to journal › Journal article › Research

    25. Published

      In vivo studies should take priority when defining mechanisms of intestinal crypt morphogenesis

      Guiu, J. & Jensen, Kim Bak, 2022, In: Cellular and Molecular Gastroenterology and Hepatology. 13, 1, 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Generation of multipotent foregut stem cells from human pluripotent stem cells

      Hannan, N. R. F., Fordham, R. P., Syed, Y. A., Moignard, V., Berry, A., Bautista, R., Hanley, N. A., Jensen, Kim Bak & Vallier, L., 2013, In: Stem Cell Reviews. 1, 4, p. 293-306 14 p.

      Research output: Contribution to journal › Journal article › Research

    27. Published

      An organoid-based CRISPR-Cas9 screen for regulators of intestinal epithelial maturation and cell fate

      Hansen, Stine Lind, Larsen, Hjalte List, Pikkupeura, Laura Maarit, Maciag, Grzegorz Jerzy, Guiu, J., Müller, I., Clement, Ditte Lynge, Mueller, C., Johansen, Jens Vilstrup, Helin, K., Lerdrup, Mads & Jensen, Kim Bak, 2023, In: Science Advances. 9, 28, 18 p., eadg4055.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Immune cell-derived signals governing epithelial phenotypes in homeostasis and inflammation

      Hausmann, Annika, Steenholdt, Casper, Nielsen, Ole Haagen & Jensen, Kim Bak, 20 Mar 2024, In: Trends in Molecular Medicine. 30, 3, p. 239-251

      Research output: Contribution to journal › Review › Research › peer-review

    29. Published

      Tuft Cells and Their Role in Intestinal Diseases

      Hendel, S. K., Kellermann, L., Hausmann, Annika, Bindslev, Niels, Jensen, Kim Bak & Nielsen, Ole Haagen, 2022, In: Frontiers in Immunology. 13, 13 p., 822867.

      Research output: Contribution to journal › Review › Research › peer-review

    30. Published

      Intestinal barrier integrity and inflammatory bowel disease: Stem cell-based approaches to regenerate the barrier

      Holmberg, F. E. O., Pedersen, J., Jørgensen, P., Soendergaard, C., Jensen, Kim Bak & Nielsen, Ole Haagen, Apr 2018, In: Journal of Tissue Engineering and Regenerative Medicine. 12, 4

      Research output: Contribution to journal › Review › Research › peer-review

    31. Rac1 deletion causes thymic atrophy

      Hunziker, L., Benitah, S. A., Aznar Benitah, S., Braun, K. M., Jensen, Kim Bak, McNulty, K., Butler, C., Potton, E., Nye, E., Boyd, R., Laurent, G., Glogauer, M., Wright, N. A., Watt, F. M. & Janes, S. M., 29 Apr 2011, In: PLOS ONE. 6, 4, p. e19292

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. A stem cell gene expression profile of human squamous cell carcinomas

      Jensen, Kim Bak, Jones, J. & Watt, F. M., 8 Dec 2008, In: Cancer Letters. 272, 1, p. 23-31 9 p.

      Research output: Contribution to journal › Journal article › Research

    33. Single-cell expression profiling of human epidermal stem and transit-amplifying cells: Lrig1 is a regulator of stem cell quiescence

      Jensen, Kim Bak & Watt, F. M., 8 Aug 2006, In: Proceedings of the National Academy of Sciences of the United States of America. 103, 32, p. 11958-63 6 p.

      Research output: Contribution to journal › Journal article › Research

    34. Lrig1 expression defines a distinct multipotent stem cell population in mammalian epidermis

      Jensen, Kim Bak, Collins, C. A., Nascimento, E., Tan, D. W., Frye, M., Itami, S. & Watt, F. M., 8 May 2009, In: Cell Stem Cell. 4, 5, p. 427-39 13 p.

      Research output: Contribution to journal › Journal article › Research

    35. Assaying proliferation and differentiation capacity of stem cells using disaggregated adult mouse epidermis

      Jensen, Kim Bak, Driskell, R. R. & Watt, F. M., May 2010, In: Nature Protocols (Online). 5, 5, p. 898-911 14 p.

      Research output: Contribution to journal › Journal article › Research

    36. Functional improvement of antibody fragments using a novel phage coat protein III fusion system

      Jensen, Kim Bak, Larsen, M., Pedersen, J. S., Christensen, P. A., Alvarez-Vallina, L., Goletz, S., Clark, B. F. C. & Kristensen, P., 8 Nov 2002, In: Molecular Cell Biology Research Communications. 298, 4, p. 566-73 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      Organoids are not organs: Sources of variation and misinformation in organoid biology

      Jensen, Kim Bak & Little, Melissa Helen, 2023, In: Stem Cell Reports. 18, 6, p. 1255-1270 16 p.

      Research output: Contribution to journal › Review › Research › peer-review

    38. Isolation of recombinant phage-displayed antibodies recognizing skin keratinocytes

      Jensen, Kim Bak & Kristensen, P., 2005, In: Methods in molecular biology (Clifton, N.J.). 289, p. 359-70 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Identification of keratinocyte-specific markers using phage display and mass spectrometry

      Jensen, Kim Bak, Jensen, O. N., Ravn, P., Clark, B. F. C. & Kristensen, P., Feb 2003, In: Molecular and Cellular Proteomics. 2, 2, p. 61-9 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      Mucosal vitamin D signaling in inflammatory bowel disease

      Kellermann, L., Jensen, Kim Bak, Bergenheim, F., Gubatan, J., Chou, N. D., Moss, A. & Nielsen, Ole Haagen, 2020, In: Autoimmunity Reviews. 19, 11, 102672.

      Research output: Contribution to journal › Review › Research › peer-review

    41. Applying phage display technology in aging research

      Kristensen, P., Ravn, P., Jensen, Kim Bak & Jensen, K., 2000, In: Biogerontology. 1, 1, p. 67-78 12 p.

      Research output: Contribution to journal › Review › Research › peer-review

    42. Published

      Reprogramming cellular identity during intestinal regeneration

      Larsen, Hjalte List & Jensen, Kim Bak, 2021, In: Current Opinion in Genetics & Development. 70, p. 40-47 8 p.

      Research output: Contribution to journal › Review › Research › peer-review

    43. Functionally fused antibodies--a novel adjuvant fusion system

      Larsen, M., Jensen, Kim Bak, Christensen, P. A., Suarez, E., Paris, D., Sanz, L., Ravn, P., Sauce, D., Saas, P., Goletz, S., Alvarez-Vallina, L. & Kristensen, P., 31 Dec 2008, In: Journal of Immunological Methods. 339, 2, p. 220-7 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      COX-2-PGE2 Signaling Impairs Intestinal Epithelial Regeneration and Associates with TNF Inhibitor Responsiveness in Ulcerative Colitis

      Li, Yuan, Soendergaard, C., Bergenheim, F. H., Aronoff, D. M., Milne, G., Riis, Lene Buhl, Seidelin, Jakob Benedict, Jensen, Kim Bak & Nielsen, Ole Haagen, 2018, In: EBioMedicine. 36, p. 497-507

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      Primary monocytes derived from ulcerative colitis show no difference in the TNF-alpha-induced immune response among responders and primary non-responders to infliximab

      Li, Y., Jensen, Kim Bak, Seidelin, Jakob Benedict & Nielsen, O. H., Sep 2017, In: Journal of Gastroenterology and Hepatology. 32, S3, p. 138-138 P-0750.

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    46. LRIG1 regulates cadherin-dependent contact inhibition directing epithelial homeostasis and pre-invasive squamous cell carcinoma development

      Lu, L., Teixeira, V. H., Yuan, Z., Graham, T. A., Endesfelder, D., Kolluri, K., Al-Juffali, N., Hamilton, N., Nicholson, A. G., Falzon, M., Kschischo, M., Swanton, C., Wright, N. A., Carroll, B., Watt, F. M., George, J. P., Jensen, Kim Bak, Giangreco, A. & Janes, S. M., Mar 2013, In: The Korean Journal of Pathology. 229, 4, p. 608-20 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      ISSCR standards for the use of human stem cells in basic research

      Ludwig, T. E., Andrews, P. W., Barbaric, I., Benvenisty, N., Bhattacharyya, A., Crook, J. M., Daheron, L. M., Draper, J. S., Healy, L. E., Huch, M., Inamdar, M. S., Jensen, K. B., Kurtz, A., Lancaster, M. A., Liberali, P., Lutolf, M. P., Mummery, C. L., Pera, M. F., Sato, Y., Shimasaki, N. & 7 others, Smith, A. G., Song, J., Spits, C., Stacey, G., Wells, C. A., Zhao, T. & Mosher, J. T., 2023, In: Stem Cell Reports. 18, 9, p. 1744-1752 9 p.

      Research output: Contribution to journal › Review › Research › peer-review

    48. Published

      Mesenchymal-epithelial crosstalk shapes intestinal regionalisation via Wnt and Shh signalling

      Maimets, Martti, Pedersen, M. T., Guiu, J., Dreier, J., Thodberg, Malte, Antoku, Yasuko, Schweiger, P. J., Rib, Leonor, Bardini Bressan, Raul, Miao, Y., Garcia, K. C., Sandelin, Albin Gustav, Serup, Palle & Jensen, Kim Bak, 2022, In: Nature Communications. 13, 12 p., 715.

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Published

      A biomechanical switch regulates the transition towards homeostasis in oesophageal epithelium

      McGinn, J., Hallou, A., Han, S., Krizic, Kata, Ulyanchenko, Svetlana, Iglesias-Bartolome, R., England, F. J., Verstreken, C., Chalut, K. J., Jensen, Kim Bak, Simons, B. D. & Alcolea, M. P., May 2021, In: Nature Cell Biology. 23, 5, p. 511-525 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      Isolation and In Vitro Characterization of Epidermal Stem Cells

      Moestrup, K. S., Andersen, M. S. & Jensen, Kim Bak, 2017, Adult Stem Cells: Methods in Molecular Biology. Paolo, D. N., Sinjiv, D. & Dinender K., S. (eds.). Humana Press, Vol. 1553. p. 67-83 17 p. (Methods in molecular biology (Clifton, N.J.)).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

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