Mette Christine Jørgensen

Mette Christine Jørgensen

ORCID: 0000-0003-2833-7863

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  1. 2023
  2. Published

    Jag1-Notch cis-interaction determines cell fate segregation in pancreatic development

    sgk681, sgk681, Seymour, Philip Allan, Sneppen, Kim, Trusina, Ala, Egeskov-Madsen, A. L. R., Jørgensen, Mette Christine, Jensen, Mogens Høgh & Serup, Palle, 2023, In: Nature Communications. 14, 17 p., 348.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. 2020
  4. Published

    Canonical Notch signaling controls the early thymic epithelial progenitor cell state and emergence of the medullary epithelial lineage in fetal thymus development

    Liu, D., Kousa, A. I., O'Neill, K. E., Rouse, P., Popis, M., Farley, A. M., Tomlinson, S. R., Ulyanchenko, Svetlana, Guillemot, F., Seymour, Philip Allan, Jørgensen, Mette Christine, Serup, Palle, Koch, U., Radtke, F. & Blackburn, C. C., 2020, In: Development (Cambridge, England). 147, p. 1-16 dev178582.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Jag1 Modulates an Oscillatory Dll1-Notch-Hes1 Signaling Module to Coordinate Growth and Fate of Pancreatic Progenitors

    Seymour, Philip Allan, Collin, C. A., Egeskov-Madsen, A. L. R., Jørgensen, Mette Christine, Shimojo, H., Imayoshi, I., de Lichtenberg, K. H., Kopan, R., Kageyama, R. & Serup, Palle, 2020, In: Developmental Cell. 52, 6, p. 731-747.e8 26 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. 2018
  7. Published

    Neurog3-dependent pancreas dysgenesis causes ectopic pancreas in Hes1 mutant mice

    Jørgensen, Mette Christine, de Lichtenberg, K. H., Collin, C. A., Klinck, R., Ekberg, J. H., Engelstoft, M. S., Lickert, H. & Serup, Palle, Sep 2018, In: Development (Cambridge, England). 145, 17, p. 1-11 11 p., dev163568.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Notch Controls Multiple Pancreatic Cell Fate Regulators Through Direct Hes1-mediated Repression

    de Lichtenberg, K. H., Seymour, Philip Allan, Jørgensen, Mette Christine, Kim, Y., Grapin-Botton, A., Magnuson, M. A., Nakic, N., Ferrer, J. & Serup, Palle, 2018, bioRxiv, 30 p. (bioRxiv, Developmental Biology).

    Research output: Working paper › Preprint › Research

  9. 2014
  10. Published

    The Prdm13 histone methyltransferase encoding gene is a Ptf1a-Rbpj downstream target that suppresses glutamatergic and promotes GABAergic neuronal fate in the dorsal neural tube

    Hanotel, J., Bessodes, N., Thélie, A., Hedderich, M., Parain, K., Driessche, B. V., Brandão, K. D. O., Kricha, S., Jørgensen, Mette Christine, Grapin-Botton, A., Serup, Palle, Lint, C. V., Perron, M., Pieler, T., Henningfeld, K. A. & Bellefroid, E. J., 15 Feb 2014, In: Developmental Biology. 386, 2, p. 340–357 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. 2012
  12. Published

    Mind bomb 1 is required for pancreatic ß-cell formation

    Horn, S., Kobberup, S., Jørgensen, Mette Christine, Kalisz, M., Klein, T., Kageyama, R., Gegg, M., Lickert, H., Lindner, J., Magnuson, M. A., Kong, Y., Serup, Palle, Ahnfelt-Rønne, J. & Jensen, J. N., 8 May 2012, In: Proceedings of the National Academy of Sciences USA (PNAS). 109, 19, p. 7356-61 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Ptf1a-mediated control of Dll1 reveals an alternative to the lateral inhibition mechanism

    Jørgensen, Mette Christine, Ahnfelt-Rønne, J., Klinck, R., Jensen, J. N., Füchtbauer, E., Deering, T., MacDonald, R. J., Wright, C. V. E., Madsen, O. D. & Serup, P., Jan 2012, In: Development. 139, 1, p. 33-45 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. 2011

  15. A BAC transgenic Hes1-EGFP reporter reveals novel expression domains in mouse embryos

    Klinck, R., Füchtbauer, E., Ahnfelt-Rønne, J., Serup, Palle, Jensen, J. N. & Jørgensen, Mette Christine, Oct 2011, In: Gene Expression Patterns. 11, 7, p. 415-26 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. 2009

  17. Retinoic acid signaling organizes endodermal organ specification along the entire antero-posterior axis

    Bayha, E., Jørgensen, Mette Christine, Serup, P. & Botton, A., 2009, In: PLOS ONE. 4, 6, p. e5845

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. 2008

  19. Specificity of four monoclonal anti-NKx6-1 antibodies

    Klinck, R., Serup, Palle, Madsen, O. D. & Jørgensen, Mette Christine, Apr 2008, In: Journal of Histochemistry and Cytochemistry. 56, 4, p. 415-24 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. 2007

  21. An illustrated review of early pancreas development in the mouse

    Jørgensen, Mette Christine, Ahnfelt-Rønne, J., Hald, J., Madsen, O. D., Serup, P. & Hecksher-Sørensen, J., Oct 2007, In: Endocrine Reviews. 28, 6, p. 685-705 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. An improved method for three-dimensional reconstruction of protein expression patterns in intact mouse and chicken embryos and organs

    Ahnfelt-Rønne, J., Jørgensen, Mette Christine, Hald, J., Madsen, O. D., Serup, P. & Hecksher-Sørensen, J., Sep 2007, In: Journal of Histochemistry and Cytochemistry. 55, 9, p. 925-30 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. 2006

  24. Generation and characterization of monoclonal antibodies against the transcription factor Nkx6.1

    Pedersen, I., Klinck, R., Hecksher-Sorensen, J., Zahn, S., Madsen, O. D., Serup, Palle & Jørgensen, Mette Christine, May 2006, In: Journal of Histochemistry and Cytochemistry. 54, 5, p. 567-74 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. 2005

  26. Endodermal expression of Nkx6 genes depends differentially on Pdx1

    Pedersen, J. K., Nelson, S. B., Jørgensen, Mette Christine, Henseleit, K. D., Fujitani, Y., Wright, C. V. E., Sander, M., Serup, P. & Beta Cell Biology Consortium, B. C. B. C., 15 Dec 2005, In: Developmental Biology. 288, 2, p. 487-501 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. 2004

  28. Gene expression profiles during beta cell maturation and after IL-1beta exposure reveal important roles of Pdx-1 and Nkx6.1 for IL-1beta sensitivity

    Nielsen, K., Kruhøffer, M., Orntoft, T., Sparre, T., Wang, H., Wollheim, C., Jørgensen, Mette Christine, Nerup, J. & Karlsen, A. E., Dec 2004, In: Diabetologia. 47, 12, p. 2185-99 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. 2000

  30. Pax4 represses pancreatic glucagon gene expression

    Petersen, H. V., Jørgensen, Mette Christine, Andersen, F. G., Jensen, J., F-Nielsen, T., Jørgensen, R., Madsen, O. D. & Serup, P., Apr 2000, In: Molecular Cell Biology Research Communications. 3, 4, p. 249-54 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. 1999

  32. Cloning and DNA-binding properties of the rat pancreatic beta-cell-specific factor Nkx6.1

    Jørgensen, Mette Christine, Vestergård Petersen, H., Ericson, J., Madsen, O. D. & Serup, P., 19 Nov 1999, In: FEBS Letters. 461, 3, p. 287-94 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. 1997

  34. Transcription factors contributing to the pancreatic beta-cell phenotype

    Madsen, O. D., Jensen, J., Petersen, H. V., Pedersen, E. E., Oster, A., Andersen, F. G., Jørgensen, Mette Christine, Jensen, P. B., Larsson, L. I. & Serup, P., Jun 1997, In: Hormone and Metabolic Research. 29, 6, p. 265-70 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. 1996
  36. Published

    Induction of insulin and islet amyloid polypeptide production in pancreatic islet glucagonoma cells by insulin promoter factor 1

    Serup, P., Jensen, J., Andersen, F. G., Jørgensen, Mette Christine, Blume, N., Holst, Jens Juul & Madsen, O. D., 20 Aug 1996, In: Proceedings of the National Academy of Sciences of the United States of America. 93, 17, p. 9015-20 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

ID: 38349911