Simultaneous disruption of PRC2 and enhancer function underlies histone H3.3-K27M oncogenic activity in human hindbrain neural stem cells

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Simultaneous disruption of PRC2 and enhancer function underlies histone H3.3-K27M oncogenic activity in human hindbrain neural stem cells. / Brien, Gerard L.; Bressan, Raul Bardini; Monger, Craig; Gannon, Dáire; Lagan, Eimear; Doherty, Anthony M.; Healy, Evan; Neikes, Hannah; Fitzpatrick, Darren J.; Deevy, Orla; Grant, Vivien; Marqués-torrejón, Maria-angeles; Alfazema, Neza; Pollard, Steven M.; Bracken, Adrian P.

In: Nature Genetics, Vol. 53, 22.07.2021, p. 1221-1232.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Brien, GL, Bressan, RB, Monger, C, Gannon, D, Lagan, E, Doherty, AM, Healy, E, Neikes, H, Fitzpatrick, DJ, Deevy, O, Grant, V, Marqués-torrejón, M, Alfazema, N, Pollard, SM & Bracken, AP 2021, 'Simultaneous disruption of PRC2 and enhancer function underlies histone H3.3-K27M oncogenic activity in human hindbrain neural stem cells', Nature Genetics, vol. 53, pp. 1221-1232. https://doi.org/10.1038/s41588-021-00897-w

APA

Brien, G. L., Bressan, R. B., Monger, C., Gannon, D., Lagan, E., Doherty, A. M., Healy, E., Neikes, H., Fitzpatrick, D. J., Deevy, O., Grant, V., Marqués-torrejón, M., Alfazema, N., Pollard, S. M., & Bracken, A. P. (2021). Simultaneous disruption of PRC2 and enhancer function underlies histone H3.3-K27M oncogenic activity in human hindbrain neural stem cells. Nature Genetics, 53, 1221-1232. https://doi.org/10.1038/s41588-021-00897-w

Vancouver

Brien GL, Bressan RB, Monger C, Gannon D, Lagan E, Doherty AM et al. Simultaneous disruption of PRC2 and enhancer function underlies histone H3.3-K27M oncogenic activity in human hindbrain neural stem cells. Nature Genetics. 2021 Jul 22;53:1221-1232. https://doi.org/10.1038/s41588-021-00897-w

Author

Brien, Gerard L. ; Bressan, Raul Bardini ; Monger, Craig ; Gannon, Dáire ; Lagan, Eimear ; Doherty, Anthony M. ; Healy, Evan ; Neikes, Hannah ; Fitzpatrick, Darren J. ; Deevy, Orla ; Grant, Vivien ; Marqués-torrejón, Maria-angeles ; Alfazema, Neza ; Pollard, Steven M. ; Bracken, Adrian P. / Simultaneous disruption of PRC2 and enhancer function underlies histone H3.3-K27M oncogenic activity in human hindbrain neural stem cells. In: Nature Genetics. 2021 ; Vol. 53. pp. 1221-1232.

Bibtex

@article{72b2aee4513146fd9583e34923e3932d,
title = "Simultaneous disruption of PRC2 and enhancer function underlies histone H3.3-K27M oncogenic activity in human hindbrain neural stem cells",
author = "Brien, {Gerard L.} and Bressan, {Raul Bardini} and Craig Monger and D{\'a}ire Gannon and Eimear Lagan and Doherty, {Anthony M.} and Evan Healy and Hannah Neikes and Fitzpatrick, {Darren J.} and Orla Deevy and Vivien Grant and Maria-angeles Marqu{\'e}s-torrej{\'o}n and Neza Alfazema and Pollard, {Steven M.} and Bracken, {Adrian P.}",
year = "2021",
month = jul,
day = "22",
doi = "10.1038/s41588-021-00897-w",
language = "English",
volume = "53",
pages = "1221--1232",
journal = "Nature Genetics",
issn = "1061-4036",
publisher = "nature publishing group",

}

RIS

TY - JOUR

T1 - Simultaneous disruption of PRC2 and enhancer function underlies histone H3.3-K27M oncogenic activity in human hindbrain neural stem cells

AU - Brien, Gerard L.

AU - Bressan, Raul Bardini

AU - Monger, Craig

AU - Gannon, Dáire

AU - Lagan, Eimear

AU - Doherty, Anthony M.

AU - Healy, Evan

AU - Neikes, Hannah

AU - Fitzpatrick, Darren J.

AU - Deevy, Orla

AU - Grant, Vivien

AU - Marqués-torrejón, Maria-angeles

AU - Alfazema, Neza

AU - Pollard, Steven M.

AU - Bracken, Adrian P.

PY - 2021/7/22

Y1 - 2021/7/22

U2 - 10.1038/s41588-021-00897-w

DO - 10.1038/s41588-021-00897-w

M3 - Journal article

C2 - 34294917

VL - 53

SP - 1221

EP - 1232

JO - Nature Genetics

JF - Nature Genetics

SN - 1061-4036

ER -

ID: 275374797