Maintenance of high-turnover tissues during and beyond homeostasis

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Maintenance of high-turnover tissues during and beyond homeostasis. / Banjac, Isidora; Maimets, Martti; Jensen, Kim B.

In: Cell Stem Cell, Vol. 30, No. 4, 2023, p. 348-361.

Research output: Contribution to journal › Review › Research › peer-review

Harvard

Banjac, I, Maimets, M & Jensen, KB 2023, 'Maintenance of high-turnover tissues during and beyond homeostasis', Cell Stem Cell, vol. 30, no. 4, pp. 348-361. https://doi.org/10.1016/j.stem.2023.03.008

APA

Banjac, I., Maimets, M., & Jensen, K. B. (2023). Maintenance of high-turnover tissues during and beyond homeostasis. Cell Stem Cell, 30(4), 348-361. https://doi.org/10.1016/j.stem.2023.03.008

Vancouver

Banjac I, Maimets M, Jensen KB. Maintenance of high-turnover tissues during and beyond homeostasis. Cell Stem Cell. 2023;30(4):348-361. https://doi.org/10.1016/j.stem.2023.03.008

Author

Banjac, Isidora ; Maimets, Martti ; Jensen, Kim B. / Maintenance of high-turnover tissues during and beyond homeostasis. In: Cell Stem Cell. 2023 ; Vol. 30, No. 4. pp. 348-361.

Bibtex

@article{fb6d63142a48475ca5a908b94eaa1ff8,
title = "Maintenance of high-turnover tissues during and beyond homeostasis",
abstract = "Tissues with a high turnover rate produce millions of cells daily and have abundant regenerative capacity. At the core of their maintenance are populations of stem cells that balance self-renewal and differentiation to produce the adequate numbers of specialized cells required for carrying out essential tissue functions. Here, we compare and contrast the intricate mechanisms and elements of homeostasis and injury-driven regeneration in the epidermis, hematopoietic system, and intestinal epithelium-the fastest renewing tissues in mammals. We highlight the functional relevance of the main mechanisms and identify open questions in the field of tissue maintenance.",
author = "Isidora Banjac and Martti Maimets and Jensen, {Kim B.}",
note = "Copyright {\textcopyright} 2023 Elsevier Inc. All rights reserved.",
year = "2023",
doi = "10.1016/j.stem.2023.03.008",
language = "English",
volume = "30",
pages = "348--361",
journal = "Cell Stem Cell",
issn = "1934-5909",
publisher = "Cell Press",
number = "4",

}

RIS

TY - JOUR

T1 - Maintenance of high-turnover tissues during and beyond homeostasis

AU - Banjac, Isidora

AU - Maimets, Martti

AU - Jensen, Kim B.

N1 - Copyright © 2023 Elsevier Inc. All rights reserved.

PY - 2023

Y1 - 2023

N2 - Tissues with a high turnover rate produce millions of cells daily and have abundant regenerative capacity. At the core of their maintenance are populations of stem cells that balance self-renewal and differentiation to produce the adequate numbers of specialized cells required for carrying out essential tissue functions. Here, we compare and contrast the intricate mechanisms and elements of homeostasis and injury-driven regeneration in the epidermis, hematopoietic system, and intestinal epithelium-the fastest renewing tissues in mammals. We highlight the functional relevance of the main mechanisms and identify open questions in the field of tissue maintenance.

AB - Tissues with a high turnover rate produce millions of cells daily and have abundant regenerative capacity. At the core of their maintenance are populations of stem cells that balance self-renewal and differentiation to produce the adequate numbers of specialized cells required for carrying out essential tissue functions. Here, we compare and contrast the intricate mechanisms and elements of homeostasis and injury-driven regeneration in the epidermis, hematopoietic system, and intestinal epithelium-the fastest renewing tissues in mammals. We highlight the functional relevance of the main mechanisms and identify open questions in the field of tissue maintenance.

U2 - 10.1016/j.stem.2023.03.008

DO - 10.1016/j.stem.2023.03.008

M3 - Review

C2 - 37028402

VL - 30

SP - 348

EP - 361

JO - Cell Stem Cell

JF - Cell Stem Cell

SN - 1934-5909

IS - 4

ER -

ID: 341789359