A bioengineering perspective on modelling the intestinal epithelial physiology in vitro

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A bioengineering perspective on modelling the intestinal epithelial physiology in vitro. / Antfolk, Maria; Jensen, Kim B.

In: Nature Communications, Vol. 11, No. 1, 6244, 07.12.2020, p. 1-11.

Research output: Contribution to journal › Review › Research › peer-review

Harvard

Antfolk, M & Jensen, KB 2020, 'A bioengineering perspective on modelling the intestinal epithelial physiology in vitro', Nature Communications, vol. 11, no. 1, 6244, pp. 1-11. https://doi.org/10.1038/s41467-020-20052-z

APA

Antfolk, M., & Jensen, K. B. (2020). A bioengineering perspective on modelling the intestinal epithelial physiology in vitro. Nature Communications, 11(1), 1-11. [6244]. https://doi.org/10.1038/s41467-020-20052-z

Vancouver

Antfolk M, Jensen KB. A bioengineering perspective on modelling the intestinal epithelial physiology in vitro. Nature Communications. 2020 Dec 7;11(1):1-11. 6244. https://doi.org/10.1038/s41467-020-20052-z

Author

Antfolk, Maria ; Jensen, Kim B. / A bioengineering perspective on modelling the intestinal epithelial physiology in vitro. In: Nature Communications. 2020 ; Vol. 11, No. 1. pp. 1-11.

Bibtex

@article{7214cc3a2fe54f9fae405eeff3c0982e,
title = "A bioengineering perspective on modelling the intestinal epithelial physiology in vitro",
abstract = "The small intestine is a specialised organ, essential for nutrient digestion and absorption. It is lined with a complex epithelial cell layer. Intestinal epithelial cells can be cultured in three-dimensional (3D) scaffolds as self-organising entities with distinct domains containing stem cells and differentiated cells. Recent developments in bioengineering provide new possibilities for directing the organisation of cells in vitro. In this Perspective, focusing on the small intestine, we discuss how studies at the interface between bioengineering and intestinal biology provide new insights into organ function. Specifically, we focus on engineered biomaterials, complex 3D structures resembling the intestinal architecture, and micro-physiological systems.",
author = "Maria Antfolk and Jensen, {Kim B}",
year = "2020",
month = dec,
day = "7",
doi = "10.1038/s41467-020-20052-z",
language = "English",
volume = "11",
pages = "1--11",
journal = "Nature Communications",
issn = "2041-1723",
publisher = "nature publishing group",
number = "1",

}

RIS

TY - JOUR

T1 - A bioengineering perspective on modelling the intestinal epithelial physiology in vitro

AU - Antfolk, Maria

AU - Jensen, Kim B

PY - 2020/12/7

Y1 - 2020/12/7

N2 - The small intestine is a specialised organ, essential for nutrient digestion and absorption. It is lined with a complex epithelial cell layer. Intestinal epithelial cells can be cultured in three-dimensional (3D) scaffolds as self-organising entities with distinct domains containing stem cells and differentiated cells. Recent developments in bioengineering provide new possibilities for directing the organisation of cells in vitro. In this Perspective, focusing on the small intestine, we discuss how studies at the interface between bioengineering and intestinal biology provide new insights into organ function. Specifically, we focus on engineered biomaterials, complex 3D structures resembling the intestinal architecture, and micro-physiological systems.

AB - The small intestine is a specialised organ, essential for nutrient digestion and absorption. It is lined with a complex epithelial cell layer. Intestinal epithelial cells can be cultured in three-dimensional (3D) scaffolds as self-organising entities with distinct domains containing stem cells and differentiated cells. Recent developments in bioengineering provide new possibilities for directing the organisation of cells in vitro. In this Perspective, focusing on the small intestine, we discuss how studies at the interface between bioengineering and intestinal biology provide new insights into organ function. Specifically, we focus on engineered biomaterials, complex 3D structures resembling the intestinal architecture, and micro-physiological systems.

U2 - 10.1038/s41467-020-20052-z

DO - 10.1038/s41467-020-20052-z

M3 - Review

C2 - 33288759

VL - 11

SP - 1

EP - 11

JO - Nature Communications

JF - Nature Communications

SN - 2041-1723

IS - 1

M1 - 6244

ER -

ID: 252880199