Kim Bak Jensen
Professor
Jensen Lab
Blegdamsvej 3B, 2200 København N
Member of:
- 2024
- Published
Immune cell-derived signals governing epithelial phenotypes in homeostasis and inflammation
Hausmann, Annika, Steenholdt, Casper, Nielsen, Ole Haagen & Jensen, Kim Bak, 20 Mar 2024, In: Trends in Molecular Medicine. 30, 3, p. 239-251Research output: Contribution to journal › Review › Research › peer-review
- 2023
- Published
Maintenance of high-turnover tissues during and beyond homeostasis
Banjac, Isidora, Maimets, Martti & Jensen, Kim Bak, 2023, In: Cell Stem Cell. 30, 4, p. 348-361 14 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Detecting host responses to microbial stimulation using primary epithelial organoids
Lange, Jette Bornholdt, Müller, C. V., Nielsen, M. J., Strickertsson, J., Rago, D., Chen, Y., Maciag, Grzegorz Jerzy, Skov, Jonathan, Wellejus, A., Schweiger, P. J., Hansen, Stine Lind, Broholm, C., Gögenur, Ismail, Maimets, Martti, Sloth, S., Hendel, J., Baker, A., Sandelin, Albin Gustav & Jensen, Kim Bak, 2023, In: Gut Microbes. 15, 2, 16 p., 2281012.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Deucravacitinib (Sotyktu™) for plaque psoriasis
Granau, Agnete Marie, Boye, T. L., Jensen, Kim Bak & Nielsen, Ole Haagen, 2023, In: Trends in Pharmacological Sciences. 44, 4, p. 252-253Research output: Contribution to journal › Letter › Research › peer-review
- Published
An organoid-based CRISPR-Cas9 screen for regulators of intestinal epithelial maturation and cell fate
Hansen, Stine Lind, Larsen, Hjalte List, Pikkupeura, Laura Maarit, Maciag, Grzegorz Jerzy, Guiu, J., Müller, I., Clement, Ditte Lynge, Mueller, C., Johansen, Jens Vilstrup, Helin, K., Lerdrup, Mads & Jensen, Kim Bak, 2023, In: Science Advances. 9, 28, 18 p., eadg4055.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Organoids are not organs: Sources of variation and misinformation in organoid biology
Jensen, Kim Bak & Little, Melissa Helen, 2023, In: Stem Cell Reports. 18, 6, p. 1255-1270 16 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
ISSCR standards for the use of human stem cells in basic research
Ludwig, T. E., Andrews, P. W., Barbaric, I., Benvenisty, N., Bhattacharyya, A., Crook, J. M., Daheron, L. M., Draper, J. S., Healy, L. E., Huch, M., Inamdar, M. S., Jensen, K. B., Kurtz, A., Lancaster, M. A., Liberali, P., Lutolf, M. P., Mummery, C. L., Pera, M. F., Sato, Y., Shimasaki, N. & 7 others, , 2023, In: Stem Cell Reports. 18, 9, p. 1744-1752 9 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Transcriptional and epigenomic profiling identifies YAP signaling as a key regulator of intestinal epithelium maturation
Pikkupeura, Laura Maarit, Bardini Bressan, Raul, Guiu, J., Chen, Y., Maimets, Martti, Mayer, Daniela, Schweiger, P. J., Hansen, Stine Lind, Maciag, Grzegorz Jerzy, Larsen, Hjalte List, Lõhmussaar, Kadi, Pedersen, M. T., Teves, Joji Marie Yap, Lange, Jette Bornholdt, Benes, V., Sandelin, Albin Gustav & Jensen, Kim Bak, 2023, In: Science Advances. 9, 28, 16 p., eadf9460.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Molecular Manipulations and Intestinal Stem Cell-Derived Organoids in Inflammatory Bowel Disease
Boye, T. L., Steenholdt, Casper, Jensen, Kim Bak & Nielsen, Ole Haagen, 2022, In: Stem Cells. 40, 5, p. 447-457Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vivo studies should take priority when defining mechanisms of intestinal crypt morphogenesis
Guiu, J. & Jensen, Kim Bak, 2022, In: Cellular and Molecular Gastroenterology and Hepatology. 13, 1, 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rebuttal to: Organoid vs Mouse Model: Which is a Better Research Tool to Understand the Biologic Mechanisms of Intestinal
Guiu, J. & Jensen, Kim Bak, 2022, In: Cellular and Molecular Gastroenterology and Hepatology. 13, 1, p. 193 1 p.Research output: Contribution to journal › Journal article › Research
- Published
Tuft Cells and Their Role in Intestinal Diseases
Hendel, S. K., Kellermann, L., Hausmann, Annika, Bindslev, Niels, Jensen, Kim Bak & Nielsen, Ole Haagen, 2022, In: Frontiers in Immunology. 13, 13 p., 822867.Research output: Contribution to journal › Review › Research › peer-review
- Published
Mesenchymal-epithelial crosstalk shapes intestinal regionalisation via Wnt and Shh signalling
Maimets, Martti, Pedersen, M. T., Guiu, J., Dreier, J., Thodberg, Malte, Antoku, Yasuko, Schweiger, P. J., Rib, Leonor, Bardini Bressan, Raul, Miao, Y., Garcia, K. C., Sandelin, Albin Gustav, Serup, Palle & Jensen, Kim Bak, 2022, In: Nature Communications. 13, 12 p., 715.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Extracellular matrix interactions provide tumor cells with an escape mechanism for commitment to differentiation
Schweiger, P. J., Le Bouteiller, M., Yui, S., Thodberg, Malte, Clement, Ditte Lynge & Jensen, Kim Bak, 2022, In: Gastroenterology. 163, 6, p. 1688-1690.e3 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lrig1 expression identifies airway basal cells with high proliferative capacity and restricts lung squamous cell carcinoma growth
Succony, L., Gómez-López, S., Pennycuick, A., Alhendi, A. S. N., Davies, D., Clarke, S. E., Gowers, K. H. C., Wright, N. A., Jensen, Kim Bak & Janes, S. M., 2022, In: European Respiratory Journal. 59, 2000816.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transplantation of intestinal organoids into a mouse model of colitis
Watanabe, S., Kobayashi, S., Ogasawara, N., Okamoto, R., Nakamura, T., Watanabe, M., Jensen, Kim Bak & Yui, S., 2022, In: Nature Protocols. 17, p. 649-671Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Reprogramming cellular identity during intestinal regeneration
Larsen, Hjalte List & Jensen, Kim Bak, 2021, In: Current Opinion in Genetics & Development. 70, p. 40-47 8 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
A biomechanical switch regulates the transition towards homeostasis in oesophageal epithelium
McGinn, J., Hallou, A., Han, S., Krizic, Kata, Ulyanchenko, Svetlana, Iglesias-Bartolome, R., England, F. J., Verstreken, C., Chalut, K. J., Jensen, Kim Bak, Simons, B. D. & Alcolea, M. P., May 2021, In: Nature Cell Biology. 23, 5, p. 511-525 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Semi-automated Organoid Screening Method Demonstrates Epigenetic Control of Intestinal Epithelial Differentiation
Ostrop, J., Zwiggelaar, R. T., Terndrup Pedersen, M., Gerbe, F., Bösl, K., Lindholm, H. T., Díez-Sánchez, A., Parmar, N., Radetzki, S., von Kries, J. P., Jay, P., Jensen, Kim Bak, Arrowsmith, C. & Oudhoff, M. J., 2021, In: Frontiers in Cell and Developmental Biology. 8, p. 1-20 618552.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
A bioengineering perspective on modelling the intestinal epithelial physiology in vitro
Antfolk, M. & Jensen, Kim Bak, 7 Dec 2020, In: Nature Communications. 11, 1, p. 1-11 6244.Research output: Contribution to journal › Review › Research › peer-review
- Published
Personalized B cell response to the Lactobacillus rhamnosus GG probiotic in healthy human subjects: a randomized trial
Lange, Jette Bornholdt, Chen, Y., Rago, Alfredo, Sloth, S., Hendel, J., Melsæther, C., Müller, C. V., Juul Nielsen, M., Strickertsson, J., Engelholm, Lars Henning, Vitting-Seerup, K., Jensen, Kim Bak, Baker, A. & Sandelin, Albin Gustav, 9 Nov 2020, In: Gut Microbes. 12, 1, p. 1-14 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mucosal vitamin D signaling in inflammatory bowel disease
Kellermann, L., Jensen, Kim Bak, Bergenheim, F., Gubatan, J., Chou, N. D., Moss, A. & Nielsen, Ole Haagen, 2020, In: Autoimmunity Reviews. 19, 11, 102672.Research output: Contribution to journal › Review › Research › peer-review
- Published
Intestinal Organoids: A Tool for Modelling Diet–Microbiome–Host Interactions
Rubert, J., Schweiger, P. J., Mattivi, F., Tuohy, K., Jensen, Kim Bak & Lunardi, A., 2020, In: Trends in Endocrinology and Metabolism. 31, 11, p. 848-858Research output: Contribution to journal › Review › Research › peer-review
- Published
LSD1 represses a neonatal/reparative gene program in adult intestinal epithelium
Zwiggelaar, R. T., Lindholm, H. T., Fosslie, M., Terndrup Pedersen, M., Ohta, Y., Díez-sánchez, A., Martín-alonso, M., Ostrop, J., Matano, M., Parmar, N., Kvaløy, E., Spanjers, R. R., Nazmi, K., Rye, M., Drabløs, F., Arrowsmith, C., Arne Dahl, J., Jensen, Kim Bak, Sato, T. & Oudhoff, M. J., 2020, In: Science Advances. 6, 37, p. 1-15 eabc0367.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Tracing the cellular dynamics of sebaceous gland development in normal and perturbed states
Andersen, M. S., Hannezo, E., Ulyanchenko, Svetlana, Estrach, S., Antoku, Yasuko, Pisano, S., Boonekamp, K. E., Sendrup, S., Maimets, Martti, Pedersen, M. T., Johansen, Jens Vilstrup, Clement, Ditte Lynge, Feral, C. C., Simons, B. D. & Jensen, Kim Bak, 2019, In: Nature Cell Biology. 21, 8, p. 924-932Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fluorescence-based tracing of transplanted intestinal epithelial cells using confocal laser endomicroscopy
Bergenheim, F., Seidelin, Jakob Benedict, Pedersen, M. T., Mead, B. E., Jensen, Kim Bak, Karp, J. M. & Nielsen, Ole Haagen, 2019, In: Stem Cell Research & Therapy. 10, 1, p. 1-12 12 p., 148.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
IL-17R–EGFR axis links wound healing to tumorigenesis in Lrig1 + stem cells
Chen, X., Cai, G., Liu, C., Zhao, J., Gu, C., Wu, L., Hamilton, T. A., Zhang, C. J., Ko, J., Zhu, L., Qin, J., Vidimos, A., Koyfman, S., Gastman, B. R., Jensen, Kim Bak & Li, X., 1 Jan 2019, In: Journal of Experimental Medicine. 216, 1, p. 195-214 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tissue-Engineering the Intestine: The Trials before the Trials
Clevers, H., Conder, R. K., Li, V. S. W., Lutolf, M. P., Vallier, L., Chan, S., Grikscheit, T. C., Jensen, Kim Bak & De Coppi, P., 6 Jun 2019, In: Cell Stem Cell. 24, 6, p. 855-859 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tracing the origin of adult intestinal stem cells
Guiu, J., Hannezo, E., Yui, S., Demharter, S., Ulyanchenko, Svetlana, Maimets, Martti, Jørgensen, A., Perlman, S., Lundvall, L., Mamsen, L. S., Larsen, A., Olesen, R. H., Andersen, C. Y., Thuesen, L. L., Hare, Kristine Juul, Pers, Tune H, Khodosevich, Konstantin, Simons, B. D. & Jensen, Kim Bak, 2019, In: Nature. 570, 7759, p. 107-111Research output: Contribution to journal › Letter › Research › peer-review
- Published
Managing vitamin D deficiency in inflammatory bowel disease
Nielsen, Ole Haagen, Hansen, T. I., Gubatan, J. M., Jensen, Kim Bak & Rejnmark, L., 2019, In: Frontline Gastroenterology. 10, 4, p. 394-400 7 p., 31656565.Research output: Contribution to journal › Review › Research › peer-review
- 2018
- Published
Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies
Boyd, M., Thodberg, M., Vitezic, M., Lange, J. B., Vitting-Seerup, K., Chen, Y., Coskun, M., Li, Y., Lo, B. Z. S., Klausen, P., Schweiger, P., Pedersen, A. G., Rapin, N. P. J-P., Skovgaard, K., Dahlgaard, K., Andersson, R., Terkelsen, T. B., Lilje, B., Troelsen, J. T., Petersen, A. M. & 7 others, , 2018, In: Nature Communications. 9, 19 p., 1661.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intestinal barrier integrity and inflammatory bowel disease: Stem cell-based approaches to regenerate the barrier
Holmberg, F. E. O., Pedersen, J., Jørgensen, P., Soendergaard, C., Jensen, Kim Bak & Nielsen, Ole Haagen, Apr 2018, In: Journal of Tissue Engineering and Regenerative Medicine. 12, 4Research output: Contribution to journal › Review › Research › peer-review
- Published
COX-2-PGE2 Signaling Impairs Intestinal Epithelial Regeneration and Associates with TNF Inhibitor Responsiveness in Ulcerative Colitis
Li, Yuan, Soendergaard, C., Bergenheim, F. H., Aronoff, D. M., Milne, G., Riis, Lene Buhl, Seidelin, Jakob Benedict, Jensen, Kim Bak & Nielsen, Ole Haagen, 2018, In: EBioMedicine. 36, p. 497-507Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dietary Control of Skin Lipid Composition and Microbiome
Moestrup, K. S., Chen, Y., Schepeler, T., Schweiger, P. J. & Jensen, Kim Bak, 2018, In: The Journal of Investigative Dermatology. 138, 5, p. 1225-1228 4 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Inhibiting RHOA Signaling in Mice Increases Glucose Tolerance and Numbers of Enteroendocrine and Other Secretory Cells in the Intestine
Petersen, N., Frimurer, Thomas Michael, Pedersen, M. T., Egerod, Kristoffer Lihme, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Grapin-Botton, A., Jensen, Kim Bak & Schwartz, Thue W., 2018, In: Gastroenterology. 155, 4, p. 1164-1176 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lrig1 marks a population of gastric epithelial cells capable of long-term tissue maintenance and growth in vitro
Schweiger, P. J., Clement, Ditte Lynge, Page, M. E., Schepeler, T., Zou, X., Sirokmány, G., Watt, F. M. & Jensen, Kim Bak, 2018, In: Scientific Reports. 8, 11 p., 15255.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration
Yui, S., Azzolin, L., Maimets, Martti, Pedersen, M. T., Fordham, R. P., Hansen, Stine Lind, Larsen, Hjalte List, Guiu, J., Alves, M. R. P., Friis, Carsten, Johansen, Jens Vilstrup, Li, Yuan, Madsen, C. D., Nakamura, T., Watanabe, M., Nielsen, Ole Haagen, Schweiger, P. J., Piccolo, S. & Jensen, Kim Bak, 1 Jan 2018, In: Cell Stem Cell. 22, 1, p. 35-49. e7 23 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
A genetically inducible porcine model of intestinal cancer
Callesen, M. M., Árnadóttir, S. S., Lyskjær, I., Ørntoft, M. B. W., Høyer, S., Dagnæs-Hansen, F., Liu, Y., Li, R., Callesen, H., Rasmussen, M. H., Berthelsen, M. F., Thomsen, M. K., Schweiger, P. J., Jensen, Kim Bak, Laurberg, S., Ørntoft, T. F., Elverløv-Jakobsen, J. E. & Andersen, C. L., Nov 2017, In: Molecular Oncology. 11, 11, p. 1616–1629 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Loss of PACS-2 delays regeneration in DSS-induced colitis but does not affect the ApcMin model of colorectal cancer
Dombernowsky, S. L., Schwarz, J., Samsøe-Petersen, Jacob, Albrechtsen, Reidar, Jensen, Kim Bak, Thomas, G. & Kveiborg, Marie, 1 Jan 2017, In: OncoTarget. 8, 65, p. 108303-108315 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Primary monocytes derived from ulcerative colitis show no difference in the TNF-alpha-induced immune response among responders and primary non-responders to infliximab
Li, Y., Jensen, Kim Bak, Seidelin, Jakob Benedict & Nielsen, O. H., Sep 2017, In: Journal of Gastroenterology and Hepatology. 32, S3, p. 138-138 P-0750.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Isolation and In Vitro Characterization of Epidermal Stem Cells
Moestrup, K. S., Andersen, M. S. & Jensen, Kim Bak, 2017, Adult Stem Cells: Methods in Molecular Biology. Paolo, D. N., Sinjiv, D. & Dinender K., S. (eds.). Humana Press, Vol. 1553. p. 67-83 17 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Cell biology: Unconventional translation in cancer
Pedersen, M. T. & Jensen, Kim Bak, 11 Jan 2017, In: Nature. 541, 7638, p. 471-472 2 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Ret receptor tyrosine kinase sustains proliferation and tissue maturation in intestinal epithelia
Perea, D., Guiu, J., Hudry, B., Konstantinidou, C., Milona, A., Hadjieconomou, D., Carroll, T., Hoyer, N., Natarajan, D., Kallijärvi, J., Walker, J. A., Soba, P., Thapar, N., Burns, A. J., Jensen, Kim Bak & Miguel-Aliaga, I., 16 Oct 2017, In: EMBO Journal. 36, 20, p. 3029-3045 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reconstruction of the mouse extrahepatic biliary tree using primary human extrahepatic cholangiocyte organoids
Sampaziotis, F., Justin, A. W., Tysoe, O. C., Sawiak, S., Godfrey, E. M., Upponi, S. S., Gieseck, R. L., de Brito, M. C., Berntsen, N. L., Gómez-Vázquez, M. J., Ortmann, D., Yiangou, L., Ross, A., Bargehr, J., Bertero, A., Zonneveld, M. C. F., Pedersen, M. T., Pawlowski, M., Valestrand, L., Madrigal, P. & 23 others, , Aug 2017, In: Nature Medicine. 23, 8, p. 954-963 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Stem cell heterogeneity revealed
Andersen, M. S. & Jensen, Kim Bak, Jun 2016, In: Nature Cell Biology. 18, 6, p. 587-9 3 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Modeling human disease using organotypic cultures
Schweiger, P. J. & Jensen, Kim Bak, Dec 2016, In: Current Opinion in Cell Biology. 43, p. 22-29 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bimodal skin progenitors-a matter of place and time
Ulyanchenko, Svetlana & Jensen, Kim Bak, 15 Dec 2016, In: E M B O Journal. 35, 24, p. 2628-2630Research output: Contribution to journal › Letter › Research
- 2015
- Published
From Definitive Endoderm to Gut-a Process of Growth and Maturation
Guiu, J. & Jensen, Kim Bak, 1 Sep 2015, In: Stem Cells and Development. 24, 17, p. 1972-83 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hippo signalling directs intestinal fate
le Bouteiller, M. C. M. & Jensen, Kim Bak, Jan 2015, In: Nature Cell Biology. 17, 1, p. 5-6 2 p.Research output: Contribution to journal › Journal article › Research
- 2014
- Published
Heterogeneity and plasticity of epidermal stem cells
Schepeler, T., Page, M. E. & Jensen, Kim Bak, Jul 2014, In: Development (Cambridge, England). 141, 13, p. 2559-2567 9 p.Research output: Contribution to journal › Review › Research › peer-review
ID: 40090325
Most downloads
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491
downloads
Ret receptor tyrosine kinase sustains proliferation and tissue maturation in intestinal epithelia
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
367
downloads
YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
256
downloads
Loss of PACS-2 delays regeneration in DSS-induced colitis but does not affect the ApcMin model of colorectal cancer
Research output: Contribution to journal › Journal article › Research › peer-review
Published