Agnete Kirkeby

Agnete Kirkeby

Guest Researcher, Associate professor, group leader, Associate Professor

Member of:

    ORCID: 0000-0001-8203-6901

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    1. Published

      Report of the international conference on manufacturing and testing of pluripotent stem cells

      Abbot, S., Agbanyo, F., Ahlfors, J-E., Baghbaderani, B. A., Bartido, S., Bharti, K., Burke, C., Carlsson, B., Cavagnaro, J., Creasey, A., Lin, S., DiGiusto, D., Francissen, K., Gaffney, A., Goldring, C., Gorba, T., Griffiths, E., Lubiniecki, A., Vandeputte, J., Hanatani, T. & 23 others, Hayakawa, T., Heki, T., Hoogendoorn, K., Kawamata, S., Kimura, H., Kirkeby, Agnete, Knezevic, I., Lebkowski, J., Lin-Gibson, S., O'Shea, O., Pera, M., Petricciani, J., Pigeau, G., Ratcliffe, A., Sato, Y., Schumann, G. G., Shingleton, W., Stacey, C. G., Sullivan, S., Svendsen, C. N., Trouvin, J., Yuan, B. & Zoon, K., Nov 2018, In: Biologicals. 63, p. 67-83

      Research output: Contribution to journal › Conference article › Research › peer-review

    2. Are Stem Cell-Based Therapies for Parkinson's Disease Ready for the Clinic in 2016?

      Barker, R. A., Parmar, M., Kirkeby, Agnete, Björklund, A., Thompson, L. & Brundin, P., 30 Mar 2016, In: Journal of Parkinson's Disease. 6, 1, p. 57-63 7 p.

      Research output: Contribution to journal › Review › Research › peer-review

    3. Published

      Target-specific forebrain projections and appropriate synaptic inputs of hESC-derived dopamine neurons grafted to the midbrain of parkinsonian rats

      Cardoso, T., Adler, A. F., Mattsson, B., Hoban, D. B., Nolbrant, S., Wahlestedt, J. N., Kirkeby, Agnete, Grealish, S., Björklund, A. & Parmar, M., 1 Sep 2018, In: The Journal of Comparative Neurology. 526, 13, p. 2133-2146

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Current advancements of modelling schizophrenia using patient-derived induced pluripotent stem cells

      Dubonyte, Ugne, Asenjo-Martinez, A., Werge, Thomas, Lage, K. & Kirkeby, Agnete, 2022, In: Acta Neuropathologica Communications. 10, 1, 20 p., 183.

      Research output: Contribution to journal › Review › Research › peer-review

    5. Published

      Human Embryonic Stem Cell-Derived Dopaminergic Grafts Alleviate L-DOPA Induced Dyskinesia

      Elabi, O. F., Pass, R., Sormonta, I., Nolbrant, S., Drummond, N., Kirkeby, Agnete, Kunath, T., Parmar, M. & Lane, E. L., 2022, In: Journal of Parkinson's Disease. 12, 6, p. 1881-1896 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Single-cell transcriptomics of human traumatic brain injury reveals activation of endogenous retroviruses in oligodendroglia

      Garza, R., Sharma, Y., Atacho, D. A. M., Thiruvalluvan, Arun, Abu Hamdeh, S., Jönsson, M. E., Horvath, V., Adami, A., Ingelsson, M., Jern, P., Hammell, M. G., Englund, E., Kirkeby, Agnete, Jakobsson, J. & Marklund, N., 2023, In: Cell Reports. 42, 11, 19 p., 113395.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Human ESC-derived dopamine neurons show similar preclinical efficacy and potency to fetal neurons when grafted in a rat model of Parkinson's disease

      Grealish, S., Diguet, E., Kirkeby, Agnete, Mattsson, B., Heuer, A., Bramoulle, Y., Van Camp, N., Perrier, A. L., Hantraye, P., Björklund, A. & Parmar, M., 1 Jan 2014, In: Cell Stem Cell. 15, 5, p. 653-665 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Monosynaptic Tracing using Modified Rabies Virus Reveals Early and Extensive Circuit Integration of Human Embryonic Stem Cell-Derived Neurons

      Grealish, S., Heuer, A., Cardoso, T., Kirkeby, Agnete, Jönsson, M., Johansson, J., Björklund, A., Jakobsson, J. & Parmar, M., 9 Jun 2015, In: Stem Cell Reports. 4, 6, p. 975-983 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. HESC-derived neural progenitors prevent xenograft rejection through neonatal desensitisation

      Heuer, A., Jönsson, M. E., Pfisterer, U., Kirkeby, Agnete & Parmar, M., 1 Aug 2016, In: Experimental Neurology. 282, p. 78-85 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Ribosomal RNA 2′-O-methylation dynamics impact cell fate decisions

      Häfner, Sophia Julia, Jansson, Martin David, Altinel, Kübra, Andersen, Kasper Langebjerg, Abay-Nørgaard, Zehra Caldwell, Ménard, Patrice, Fontenas, M., Sørensen, Daniel Madriz, Gay, David Michael, Arendrup, Frederic Schrøder, Tehler, D., Krogh, Nicolai, Nielsen, Henrik, Kraushar, M. L., Kirkeby, Agnete & Lund, Anders H., 2023, In: Developmental Cell. 58, 17, p. 1593-1609.e9

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      MSLibrarian: Optimized Predicted Spectral Libraries for Data-Independent Acquisition Proteomics

      Isaksson, M., Karlsson, C., Laurell, T., Kirkeby, Agnete & Heusel, M., 2022, In: Journal of Proteome Research. 21, 2, p. 535–546 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Comprehensive analysis of microrna expression in regionalized human neural progenitor cells reveals microRNA-10 as a caudalizing factor

      Jönsson, M. E., Wahlestedt, J. N., Åkerblom, M., Kirkeby, Agnete, Malmevik, J., Brattaas, P. L., Jakobsson, J. & Parmar, M., 23 Sep 2015, In: Development (Cambridge). 142, 18, p. 3166-3177 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Single-Cell Analysis Reveals a Close Relationship between Differentiating Dopamine and Subthalamic Nucleus Neuronal Lineages.

      Kee, N., Volakakis, N., Kirkeby, Agnete, Dahl, L., Storvall, H., Nolbrant, S., Lahti, L., Bjoerklund, A. K., Gillberg, L., Joodmardi, E., Sandberg, R., Parmar, M. & Perlmann, T., 5 Jan 2017, In: Cell Stem Cell. 20, 1, p. 29-40 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Preclinical assessment of a pluripotent cell therapy for treatment of Parkinson's Disease

      Kirkeby, Agnete, 2021, In: Toxicology Letters. 350, Supplement, p. S37 1 p.

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    15. Published

      Building authentic midbrain dopaminergic neurons from stem CEllS - Lessons from development

      Kirkeby, Agnete & Parmar, M., 1 Dec 2012, In: Translational Neuroscience. 3, 4, p. 314-319 6 p.

      Research output: Contribution to journal › Review › Research › peer-review

    16. Published

      Parkinson disease and growth factors — is GDNF good enough?

      Kirkeby, Agnete & Barker, R. A., 1 Jun 2019, In: Nature Reviews Neurology. 15, 6, p. 312-314 3 p.

      Research output: Contribution to journal › Comment/debate › Research › peer-review

    17. Published

      Functional and immunochemical characterisation of different antibodies against the erythropoietin receptor

      Kirkeby, Agnete, van Beek, J., Nielsen, J., Leist, M. & Helboe, L., 15 Aug 2007, In: Journal of Neuroscience Methods. 164, 1, p. 50-58 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Generation of Regionally Specified Neural Progenitors and Functional Neurons from Human Embryonic Stem Cells under Defined Conditions

      Kirkeby, Agnete, Grealish, S., Wolf, D. A., Nelander, J., Wood, J., Lundblad, M., Lindvall, O. & Parmar, M., 28 Jun 2012, In: Cell Reports. 1, 6, p. 703-714 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Predictive Markers Guide Differentiation to Improve Graft Outcome in Clinical Translation of hESC-Based Therapy for Parkinson's Disease.

      Kirkeby, Agnete, Nolbrant, S., Tiklova, K., Heuer, A., Kee, N., Cardoso, T., Ottosson, D. R., Lelos, M. J., Rifes, P., Dunnett, S. B., Grealish, S., Perlmann, T. & Parmar, M., 2017, In: Cell Stem Cell. 20, 1, p. 135-148 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      The stem cell niche finds its true north

      Kirkeby, Agnete, Perlmann, T. & Pereira, C. F., 15 Aug 2016, In: Development (Cambridge). 143, 16, p. 2877-2881 5 p.

      Research output: Contribution to journal › Review › Research › peer-review

    21. Strategies for bringing stem cell-derived dopamine neurons to the clinic: A European approach (STEM-PD)

      Kirkeby, Agnete, Parmar, M. & Barker, R. A., 2017, Functional Neural Transplantation IV: Translation to Clinical Application, Part A. Vol. 230. p. 165-190 26 p. (Progress in Brain Research).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    22. Published

      Generating regionalized neuronal cells from pluripotency, a step-by-stepprotocol

      Kirkeby, Agnete, Nelander, J. & Parmar, M., 3 Jan 2013, In: Frontiers in Cellular Neuroscience. JANUARY 2013

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      High-dose erythropoietin alters platelet reactivity and bleeding time in rodents in contrast to the neuroprotective variant carbamyl-erythropoietin (CEPO).

      Kirkeby, Agnete, Torup, L., Bochsen, L., Kjalke, M., Abel, K., Theilgaard-Mønch, Kim, Johansson, P. I., Bjørn, S. E., Gerwien, J. & Leist, M., 2008, In: Thrombosis and Haemostasis. 99, 4, p. 720-8 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Preclinical quality, safety, and efficacy of a human embryonic stem cell-derived product for the treatment of Parkinson's disease, STEM-PD

      Novo Nordisk Cell Therapy R&D, N. N. C. T. R., 2023, In: Cell Stem Cell. 30, 10, p. 1299-1314.e9 17 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Genetic modification increases the survival and the neuroregenerative properties of transplanted neural stem cells

      Korshunova, Irina, Rhein, S., vsz834, vsz834, Stölting, I., Pfisterer, U., Barta, A., Dmytriyeva, O., Kirkeby, Agnete, Schwaninger, M. & Khodosevich, Konstantin, 2020, In: JCI insight. 5, 4, p. 1-19 e126268.

      Research output: Contribution to journal › Journal article › Research › peer-review

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