Agnete Kirkeby

Agnete Kirkeby

Guest Researcher, Associate professor, group leader, Associate Professor

Member of:


    1. 2024
    2. E-pub ahead of print

      Good Manufacturing Practice–compliant human induced pluripotent stem cells: from bench to putative clinical products

      Novoa, J. J., Westra, I. M., Steeneveld, E., Fonseca Neves, N., Arendzen, C. H., Rajaei, B., Grundeken, E., Yildiz, M., van der Valk, W., Salvador, A., Carlotti, F., Dijkers, P. F., Locher, H., van den Berg, C. W., Raymond, K. I., Kirkeby, A., Mummery, C. L., Rabelink, T. J., Freund, C., Meij, P. & 1 others, Wieles, B., 2024, (E-pub ahead of print) In: Cytotherapy.

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. 2023
    4. Published

      Single-cell transcriptomics of human traumatic brain injury reveals activation of endogenous retroviruses in oligodendroglia

      Garza, R., Sharma, Y., Atacho, D. A. M., Thiruvalluvan, Arun, Abu Hamdeh, S., Jönsson, M. E., Horvath, V., Adami, A., Ingelsson, M., Jern, P., Hammell, M. G., Englund, E., Kirkeby, Agnete, Jakobsson, J. & Marklund, N., 2023, In: Cell Reports. 42, 11, 19 p., 113395.

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. Published
    6. Published

      Preclinical quality, safety, and efficacy of a human embryonic stem cell-derived product for the treatment of Parkinson's disease, STEM-PD

      Novo Nordisk Cell Therapy R&D, N. N. C. T. R., 2023, In: Cell Stem Cell. 30, 10, p. 1299-1314.e9 17 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. Published

      Characterising the RNA-binding protein atlas of the mammalian brain uncovers RBM5 misregulation in mouse models of Huntington's disease

      Mullari, M., Fossat, Nicolas Julien, Skotte, Niels Henning, Asenjo-Martinez, A., Humphreys, D. T., Bukh, Jens, Kirkeby, Agnete, Scheel, Troels Kasper Høyer & Nielsen, Michael Lund, 2023, In: Nature Communications. 14, 20 p., 4348.

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Published

      Identifying secreted biomarkers of dopaminergic ventral midbrain progenitor cells

      Rifes, P., Isaksson, M., Rusimbi, Charlotte Nuru, Ramón Santonja, A., Nelander, J., Laurell, T. & Kirkeby, Agnete, 2023, In: Stem Cell Research and Therapy. 14, 1, 354.

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. 2022
    10. Published

      Current advancements of modelling schizophrenia using patient-derived induced pluripotent stem cells

      Dubonyte, Ugne, Asenjo-Martinez, A., Werge, Thomas, Lage, K. & Kirkeby, Agnete, 2022, In: Acta Neuropathologica Communications. 10, 1, 20 p., 183.

      Research output: Contribution to journalReviewResearchpeer-review

    11. Published

      Human Embryonic Stem Cell-Derived Dopaminergic Grafts Alleviate L-DOPA Induced Dyskinesia

      Elabi, O. F., Pass, R., Sormonta, I., Nolbrant, S., Drummond, N., Kirkeby, Agnete, Kunath, T., Parmar, M. & Lane, E. L., 2022, In: Journal of Parkinson's Disease. 12, 6, p. 1881-1896 16 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. Published

      MSLibrarian: Optimized Predicted Spectral Libraries for Data-Independent Acquisition Proteomics

      Isaksson, M., Karlsson, C., Laurell, T., Kirkeby, Agnete & Heusel, M., 2022, In: Journal of Proteome Research. 21, 2, p. 535–546 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    13. 2021
    14. Published

      Preclinical assessment of a pluripotent cell therapy for treatment of Parkinson's Disease

      Kirkeby, Agnete, 2021, In: Toxicology Letters. 350, Supplement, p. S37 1 p.

      Research output: Contribution to journalConference abstract in journalResearchpeer-review

    15. Published

      Bringing Advanced Therapies for Parkinson's Disease to the Clinic: The Scientist's Perspective

      Tomishima, M. & Kirkeby, Agnete, 2021, In: Journal of Parkinson's Disease. 11, p. S135-S140 6 p.

      Research output: Contribution to journalReviewResearchpeer-review

    16. 2020
    17. Published

      Genetic modification increases the survival and the neuroregenerative properties of transplanted neural stem cells

      Korshunova, Irina, Rhein, S., vsz834, vsz834, Stölting, I., Pfisterer, U., Barta, A., Dmytriyeva, O., Kirkeby, Agnete, Schwaninger, M. & Khodosevich, Konstantin, 2020, In: JCI insight. 5, 4, p. 1-19 e126268.

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. Published

      Modeling neural tube development by differentiation of human embryonic stem cells in a microfluidic WNT gradient

      Rifes, P., Isaksson, M., Rathore, Gaurav Singh, Aldrin-Kirk, P., Moller, O. K., Barzaghi, G., Lee, J., Egerod, Kristoffer Lihme, Belmont-Rausch, Dylan Matthew, Parmar, M., Pers, Tune H, Laurell, T. & Kirkeby, Agnete, 2020, In: Nature Biotechnology. 38, p. 1265-1273 9 p.

      Research output: Contribution to journalLetterResearchpeer-review

    19. Published

      Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson’s disease

      Tiklová, K., Nolbrant, S., Fiorenzano, A., Björklund, Å. K., Sharma, Y., Heuer, A., Gillberg, L., Hoban, D. B., Cardoso, T., Adler, A. F., Birtele, M., Lundén-Miguel, H., Volakakis, N., Kirkeby, Agnete, Perlmann, T. & Parmar, M., 1 Dec 2020, In: Nature Communications. 11, 1, 11 p., 2434.

      Research output: Contribution to journalJournal articleResearchpeer-review

    20. 2019
    21. Published

      Parkinson disease and growth factors — is GDNF good enough?

      Kirkeby, Agnete & Barker, R. A., 1 Jun 2019, In: Nature Reviews Neurology. 15, 6, p. 312-314 3 p.

      Research output: Contribution to journalComment/debateResearchpeer-review

    22. 2018
    23. Published

      Report of the international conference on manufacturing and testing of pluripotent stem cells

      Abbot, S., Agbanyo, F., Ahlfors, J-E., Baghbaderani, B. A., Bartido, S., Bharti, K., Burke, C., Carlsson, B., Cavagnaro, J., Creasey, A., Lin, S., DiGiusto, D., Francissen, K., Gaffney, A., Goldring, C., Gorba, T., Griffiths, E., Lubiniecki, A., Vandeputte, J., Hanatani, T. & 23 others, Hayakawa, T., Heki, T., Hoogendoorn, K., Kawamata, S., Kimura, H., Kirkeby, Agnete, Knezevic, I., Lebkowski, J., Lin-Gibson, S., O'Shea, O., Pera, M., Petricciani, J., Pigeau, G., Ratcliffe, A., Sato, Y., Schumann, G. G., Shingleton, W., Stacey, C. G., Sullivan, S., Svendsen, C. N., Trouvin, J., Yuan, B. & Zoon, K., Nov 2018, In: Biologicals. 63, p. 67-83

      Research output: Contribution to journalConference articleResearchpeer-review

    24. Published

      Target-specific forebrain projections and appropriate synaptic inputs of hESC-derived dopamine neurons grafted to the midbrain of parkinsonian rats

      Cardoso, T., Adler, A. F., Mattsson, B., Hoban, D. B., Nolbrant, S., Wahlestedt, J. N., Kirkeby, Agnete, Grealish, S., Björklund, A. & Parmar, M., 1 Sep 2018, In: The Journal of Comparative Neurology. 526, 13, p. 2133-2146

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. Published

      Sense-Antisense lncRNA Pair Encoded by Locus 6p22.3 Determines Neuroblastoma Susceptibility via the USP36-CHD7-SOX9 Regulatory Axis

      Mondal, T., Juvvuna, P. K., Kirkeby, A., Mitra, S., Kosalai, S. T., Traxler, L., Hertwig, F., Wernig-Zorc, S., Miranda, C., Deland, L., Volland, R., Bartenhagen, C., Bartsch, D., Bandaru, S., Engesser, A., Subhash, S., Martinsson, T., Carén, H., Akyürek, L. M., Kurian, L. & 5 others, Kanduri, M., Huarte, M., Kogner, P., Fischer, M. & Kanduri, C., 12 Mar 2018, In: Cancer Cell. 33, 3, p. 417-434.e7

      Research output: Contribution to journalJournal articleResearchpeer-review

    26. Published

      A symphony of stem cells in Vienna - looking to the future

      Porrello, E. R. & Kirkeby, Agnete, 8 Jun 2018, In: Development (Cambridge, England). 145, 11, 6 p., 163501.

      Research output: Contribution to journalConference articleResearchpeer-review

    27. 2017
    28. Published

      Single-Cell Analysis Reveals a Close Relationship between Differentiating Dopamine and Subthalamic Nucleus Neuronal Lineages.

      Kee, N., Volakakis, N., Kirkeby, Agnete, Dahl, L., Storvall, H., Nolbrant, S., Lahti, L., Bjoerklund, A. K., Gillberg, L., Joodmardi, E., Sandberg, R., Parmar, M. & Perlmann, T., 5 Jan 2017, In: Cell Stem Cell. 20, 1, p. 29-40 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    29. Predictive Markers Guide Differentiation to Improve Graft Outcome in Clinical Translation of hESC-Based Therapy for Parkinson's Disease.

      Kirkeby, Agnete, Nolbrant, S., Tiklova, K., Heuer, A., Kee, N., Cardoso, T., Ottosson, D. R., Lelos, M. J., Rifes, P., Dunnett, S. B., Grealish, S., Perlmann, T. & Parmar, M., 2017, In: Cell Stem Cell. 20, 1, p. 135-148 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    30. Strategies for bringing stem cell-derived dopamine neurons to the clinic: A European approach (STEM-PD)

      Kirkeby, Agnete, Parmar, M. & Barker, R. A., 2017, Functional Neural Transplantation IV: Translation to Clinical Application, Part A. Vol. 230. p. 165-190 26 p. (Progress in Brain Research).

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    31. Published

      IAP-Based Cell Sorting Results in Homogeneous Transplantable Dopaminergic Precursor Cells Derived from Human Pluripotent Stem Cells.

      Lehnen, D., Barral, S., Cardoso, T., Grealish, S., Heuer, A., Smiyakin, A., Kirkeby, Agnete, Kollet, J., Cremer, H., Parmar, M., Bosio, A. & Knoebel, S., Oct 2017, In: Stem Cell Reports. 9, 4, p. 1207-1220 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    32. Published
    33. Term amniotic fluid: an unexploited reserve of mesenchymal stromal cells for reprogramming and potential cell therapy applications.

      Moraghebi, R., Kirkeby, Agnete, Chaves, P., Roenn, R. E., Sitnicka, E., Parmar, M., Larsson, M., Herbst, A. & Woods, N., 25 Aug 2017, In: Stem Cell Research & Therapy. 8, 12 p., 190.

      Research output: Contribution to journalJournal articleResearchpeer-review

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