Agnete Kirkeby

Agnete Kirkeby

Guest Researcher, Associate professor, group leader, Associate Professor

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    ORCID: 0000-0001-8203-6901

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    1. Published

      Tracking differentiating neural progenitors in pluripotent cultures using microRNA-regulated lentiviral vectors

      Sachdeva, R., Jönsson, M. E., Nelander, J., Kirkeby, Agnete, Guibentif, C., Gentner, B., Naldini, L., Björklund, A., Parmar, M. & Jakobsson, J., 22 Jun 2010, In: Proceedings of the National Academy of Sciences of the United States of America. 107, 25, p. 11602-11607 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      Therapeutic window for nonerythropoietic carbamylated-erythropoietin to improve motor function following multiple infarct ischemic strokes in New Zealand white rabbits

      Lapchak, P. A., Kirkeby, Agnete, Zivin, J. A. & Sager, T. N., 31 Oct 2008, In: Brain Research. 1238, p. 208-214 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      The stem cell niche finds its true north

      Kirkeby, Agnete, Perlmann, T. & Pereira, C. F., 15 Aug 2016, In: Development (Cambridge). 143, 16, p. 2877-2881 5 p.

      Research output: Contribution to journal › Review › Research › peer-review

    4. Published

      The biological and ethical basis of the use of human embryonic stem cells for in vitro test systems or cell therapy

      Leist, M., Bremer, S., Brundin, P., Hescheler, J., Kirkeby, Agnete, Krause, K. H., Pörzgen, P., Pucéat, M., Schmidt, M., Schrattenholz, A., Zak, N. B. & Hentze, H., 1 Dec 2008, In: Altex. 25, 3, p. 163-190 28 p.

      Research output: Contribution to journal › Review › Research › peer-review

    5. Term amniotic fluid: an unexploited reserve of mesenchymal stromal cells for reprogramming and potential cell therapy applications.

      Moraghebi, R., Kirkeby, Agnete, Chaves, P., Roenn, R. E., Sitnicka, E., Parmar, M., Larsson, M., Herbst, A. & Woods, N., 25 Aug 2017, In: Stem Cell Research & Therapy. 8, 12 p., 190.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Target-specific forebrain projections and appropriate synaptic inputs of hESC-derived dopamine neurons grafted to the midbrain of parkinsonian rats

      Cardoso, T., Adler, A. F., Mattsson, B., Hoban, D. B., Nolbrant, S., Wahlestedt, J. N., Kirkeby, Agnete, Grealish, S., Björklund, A. & Parmar, M., 1 Sep 2018, In: The Journal of Comparative Neurology. 526, 13, p. 2133-2146

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Strategies for bringing stem cell-derived dopamine neurons to the clinic: A European approach (STEM-PD)

      Kirkeby, Agnete, Parmar, M. & Barker, R. A., 2017, Functional Neural Transplantation IV: Translation to Clinical Application, Part A. Vol. 230. p. 165-190 26 p. (Progress in Brain Research).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    8. Published

      Single-cell transcriptomics of human traumatic brain injury reveals activation of endogenous retroviruses in oligodendroglia

      Garza, R., Sharma, Y., Atacho, D. A. M., Thiruvalluvan, Arun, Abu Hamdeh, S., Jönsson, M. E., Horvath, V., Adami, A., Ingelsson, M., Jern, P., Hammell, M. G., Englund, E., Kirkeby, Agnete, Jakobsson, J. & Marklund, N., 2023, In: Cell Reports. 42, 11, 19 p., 113395.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Single-Cell Analysis Reveals a Close Relationship between Differentiating Dopamine and Subthalamic Nucleus Neuronal Lineages.

      Kee, N., Volakakis, N., Kirkeby, Agnete, Dahl, L., Storvall, H., Nolbrant, S., Lahti, L., Bjoerklund, A. K., Gillberg, L., Joodmardi, E., Sandberg, R., Parmar, M. & Perlmann, T., 5 Jan 2017, In: Cell Stem Cell. 20, 1, p. 29-40 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson’s disease

      Tiklová, K., Nolbrant, S., Fiorenzano, A., Björklund, Å. K., Sharma, Y., Heuer, A., Gillberg, L., Hoban, D. B., Cardoso, T., Adler, A. F., Birtele, M., Lundén-Miguel, H., Volakakis, N., Kirkeby, Agnete, Perlmann, T. & Parmar, M., 1 Dec 2020, In: Nature Communications. 11, 1, 11 p., 2434.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Sense-Antisense lncRNA Pair Encoded by Locus 6p22.3 Determines Neuroblastoma Susceptibility via the USP36-CHD7-SOX9 Regulatory Axis

      Mondal, T., Juvvuna, P. K., Kirkeby, A., Mitra, S., Kosalai, S. T., Traxler, L., Hertwig, F., Wernig-Zorc, S., Miranda, C., Deland, L., Volland, R., Bartenhagen, C., Bartsch, D., Bandaru, S., Engesser, A., Subhash, S., Martinsson, T., Carén, H., Akyürek, L. M., Kurian, L. & 5 others, Kanduri, M., Huarte, M., Kogner, P., Fischer, M. & Kanduri, C., 12 Mar 2018, In: Cancer Cell. 33, 3, p. 417-434.e7

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Ribosomal RNA 2′-O-methylation dynamics impact cell fate decisions

      Häfner, Sophia Julia, Jansson, Martin David, Altinel, Kübra, Andersen, Kasper Langebjerg, Abay-Nørgaard, Zehra Caldwell, Ménard, Patrice, Fontenas, M., Sørensen, Daniel Madriz, Gay, David Michael, Arendrup, Frederic Schrøder, Tehler, D., Krogh, Nicolai, Nielsen, Henrik, Kraushar, M. L., Kirkeby, Agnete & Lund, Anders H., 2023, In: Developmental Cell. 58, 17, p. 1593-1609.e9

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Report of the international conference on manufacturing and testing of pluripotent stem cells

      Abbot, S., Agbanyo, F., Ahlfors, J-E., Baghbaderani, B. A., Bartido, S., Bharti, K., Burke, C., Carlsson, B., Cavagnaro, J., Creasey, A., Lin, S., DiGiusto, D., Francissen, K., Gaffney, A., Goldring, C., Gorba, T., Griffiths, E., Lubiniecki, A., Vandeputte, J., Hanatani, T. & 23 others, Hayakawa, T., Heki, T., Hoogendoorn, K., Kawamata, S., Kimura, H., Kirkeby, Agnete, Knezevic, I., Lebkowski, J., Lin-Gibson, S., O'Shea, O., Pera, M., Petricciani, J., Pigeau, G., Ratcliffe, A., Sato, Y., Schumann, G. G., Shingleton, W., Stacey, C. G., Sullivan, S., Svendsen, C. N., Trouvin, J., Yuan, B. & Zoon, K., Nov 2018, In: Biologicals. 63, p. 67-83

      Research output: Contribution to journal › Conference article › Research › peer-review

    14. Predictive Markers Guide Differentiation to Improve Graft Outcome in Clinical Translation of hESC-Based Therapy for Parkinson's Disease.

      Kirkeby, Agnete, Nolbrant, S., Tiklova, K., Heuer, A., Kee, N., Cardoso, T., Ottosson, D. R., Lelos, M. J., Rifes, P., Dunnett, S. B., Grealish, S., Perlmann, T. & Parmar, M., 2017, In: Cell Stem Cell. 20, 1, p. 135-148 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Preclinical quality, safety, and efficacy of a human embryonic stem cell-derived product for the treatment of Parkinson's disease, STEM-PD

      Parmar, M., Novo Nordisk Cell Therapy R&D, N. N. C. T. R. & Christiansen, Josefine Rågård, 2023, In: Cell Stem Cell. 30, 10, p. 1299-1314.e9 17 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Preclinical assessment of a pluripotent cell therapy for treatment of Parkinson's Disease

      Kirkeby, Agnete, 2021, In: Toxicology Letters. 350, Supplement, p. S37 1 p.

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    17. Published

      Parkinson disease and growth factors — is GDNF good enough?

      Kirkeby, Agnete & Barker, R. A., 1 Jun 2019, In: Nature Reviews Neurology. 15, 6, p. 312-314 3 p.

      Research output: Contribution to journal › Comment/debate › Research › peer-review

    18. Published

      Monosynaptic Tracing using Modified Rabies Virus Reveals Early and Extensive Circuit Integration of Human Embryonic Stem Cell-Derived Neurons

      Grealish, S., Heuer, A., Cardoso, T., Kirkeby, Agnete, Jönsson, M., Johansson, J., Björklund, A., Jakobsson, J. & Parmar, M., 9 Jun 2015, In: Stem Cell Reports. 4, 6, p. 975-983 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Modeling neural tube development by differentiation of human embryonic stem cells in a microfluidic WNT gradient

      Rifes, P., Isaksson, M., Rathore, Gaurav Singh, Aldrin-Kirk, P., Moller, O. K., Barzaghi, G., Lee, J., Egerod, Kristoffer Lihme, Belmont-Rausch, Dylan Matthew, Parmar, M., Pers, Tune H, Laurell, T. & Kirkeby, Agnete, 2020, In: Nature Biotechnology. 38, p. 1265-1273 9 p.

      Research output: Contribution to journal › Letter › Research › peer-review

    20. Published

      MSLibrarian: Optimized Predicted Spectral Libraries for Data-Independent Acquisition Proteomics

      Isaksson, M., Karlsson, C., Laurell, T., Kirkeby, Agnete & Heusel, M., 2022, In: Journal of Proteome Research. 21, 2, p. 535–546 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Identifying secreted biomarkers of dopaminergic ventral midbrain progenitor cells

      Rifes, P., Isaksson, M., Rusimbi, Charlotte Nuru, Ramón Santonja, A., Nelander, J., Laurell, T. & Kirkeby, Agnete, 2023, In: Stem Cell Research and Therapy. 14, 1, 354.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      IAP-Based Cell Sorting Results in Homogeneous Transplantable Dopaminergic Precursor Cells Derived from Human Pluripotent Stem Cells.

      Lehnen, D., Barral, S., Cardoso, T., Grealish, S., Heuer, A., Smiyakin, A., Kirkeby, Agnete, Kollet, J., Cremer, H., Parmar, M., Bosio, A. & Knoebel, S., Oct 2017, In: Stem Cell Reports. 9, 4, p. 1207-1220 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Human Embryonic Stem Cell-Derived Dopaminergic Grafts Alleviate L-DOPA Induced Dyskinesia

      Elabi, O. F., Pass, R., Sormonta, I., Nolbrant, S., Drummond, N., Kirkeby, Agnete, Kunath, T., Parmar, M. & Lane, E. L., 2022, In: Journal of Parkinson's Disease. 12, 6, p. 1881-1896 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Human ESC-derived dopamine neurons show similar preclinical efficacy and potency to fetal neurons when grafted in a rat model of Parkinson's disease

      Grealish, S., Diguet, E., Kirkeby, Agnete, Mattsson, B., Heuer, A., Bramoulle, Y., Van Camp, N., Perrier, A. L., Hantraye, P., Björklund, A. & Parmar, M., 1 Jan 2014, In: Cell Stem Cell. 15, 5, p. 653-665 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      High-dose erythropoietin alters platelet reactivity and bleeding time in rodents in contrast to the neuroprotective variant carbamyl-erythropoietin (CEPO).

      Kirkeby, Agnete, Torup, L., Bochsen, L., Kjalke, M., Abel, K., Theilgaard-Mønch, Kim, Johansson, P. I., Bjørn, S. E., Gerwien, J. & Leist, M., 2008, In: Thrombosis and Haemostasis. 99, 4, p. 720-8 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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    ID: 172979835