Agnete Kirkeby
Guest Researcher, Associate professor, group leader, Associate Professor
Developmental Neuroscience
Blegdamsvej 3B
2200 København N
Kirkeby Lab
Blegdamsvej 3
2200 København N
Member of:
- Published
Report of the international conference on manufacturing and testing of pluripotent stem cells
Abbot, S., Agbanyo, F., Ahlfors, J-E., Baghbaderani, B. A., Bartido, S., Bharti, K., Burke, C., Carlsson, B., Cavagnaro, J., Creasey, A., Lin, S., DiGiusto, D., Francissen, K., Gaffney, A., Goldring, C., Gorba, T., Griffiths, E., Lubiniecki, A., Vandeputte, J., Hanatani, T. & 23 others, , Nov 2018, In: Biologicals. 63, p. 67-83Research output: Contribution to journal › Conference article › Research › peer-review
Are Stem Cell-Based Therapies for Parkinson's Disease Ready for the Clinic in 2016?
Barker, R. A., Parmar, M., Kirkeby, Agnete, Björklund, A., Thompson, L. & Brundin, P., 30 Mar 2016, In: Journal of Parkinson's Disease. 6, 1, p. 57-63 7 p.Research output: Contribution to journal › Review › Research › peer-review
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Target-specific forebrain projections and appropriate synaptic inputs of hESC-derived dopamine neurons grafted to the midbrain of parkinsonian rats
Cardoso, T., Adler, A. F., Mattsson, B., Hoban, D. B., Nolbrant, S., Wahlestedt, J. N., Kirkeby, Agnete, Grealish, S., Björklund, A. & Parmar, M., 1 Sep 2018, In: The Journal of Comparative Neurology. 526, 13, p. 2133-2146Research output: Contribution to journal › Journal article › Research › peer-review
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Clinical translation of pluripotent stem cell-based therapies: successes and challenges
Christiansen, Josefine Rågård & Kirkeby, Agnete, 1 Apr 2024, In: Development (Cambridge, England). 151, 7Research output: Contribution to journal › Journal article › Research › peer-review
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Current advancements of modelling schizophrenia using patient-derived induced pluripotent stem cells
Dubonyte, Ugne, Asenjo-Martinez, A., Werge, Thomas, Lage, K. & Kirkeby, Agnete, 2022, In: Acta Neuropathologica Communications. 10, 1, 20 p., 183.Research output: Contribution to journal › Review › Research › peer-review
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Human Embryonic Stem Cell-Derived Dopaminergic Grafts Alleviate L-DOPA Induced Dyskinesia
Elabi, O. F., Pass, R., Sormonta, I., Nolbrant, S., Drummond, N., Kirkeby, Agnete, Kunath, T., Parmar, M. & Lane, E. L., 2022, In: Journal of Parkinson's Disease. 12, 6, p. 1881-1896 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Single-cell transcriptomics of human traumatic brain injury reveals activation of endogenous retroviruses in oligodendroglia
Garza, R., Sharma, Y., Atacho, D. A. M., Thiruvalluvan, Arun, Abu Hamdeh, S., Jönsson, M. E., Horvath, V., Adami, A., Ingelsson, M., Jern, P., Hammell, M. G., Englund, E., Kirkeby, Agnete, Jakobsson, J. & Marklund, N., 2023, In: Cell Reports. 42, 11, 19 p., 113395.Research output: Contribution to journal › Journal article › Research › peer-review
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Human ESC-derived dopamine neurons show similar preclinical efficacy and potency to fetal neurons when grafted in a rat model of Parkinson's disease
Grealish, S., Diguet, E., Kirkeby, Agnete, Mattsson, B., Heuer, A., Bramoulle, Y., Van Camp, N., Perrier, A. L., Hantraye, P., Björklund, A. & Parmar, M., 1 Jan 2014, In: Cell Stem Cell. 15, 5, p. 653-665 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Monosynaptic Tracing using Modified Rabies Virus Reveals Early and Extensive Circuit Integration of Human Embryonic Stem Cell-Derived Neurons
Grealish, S., Heuer, A., Cardoso, T., Kirkeby, Agnete, Jönsson, M., Johansson, J., Björklund, A., Jakobsson, J. & Parmar, M., 9 Jun 2015, In: Stem Cell Reports. 4, 6, p. 975-983 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
HESC-derived neural progenitors prevent xenograft rejection through neonatal desensitisation
Heuer, A., Jönsson, M. E., Pfisterer, U., Kirkeby, Agnete & Parmar, M., 1 Aug 2016, In: Experimental Neurology. 282, p. 78-85 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ribosomal RNA 2′-O-methylation dynamics impact cell fate decisions
Häfner, Sophia Julia, Jansson, Martin David, Altinel, Kübra, Andersen, Kasper Langebjerg, Abay-Nørgaard, Zehra Caldwell, Ménard, Patrice, Fontenas, M., Sørensen, Daniel Madriz, Gay, David Michael, Arendrup, Frederic Schrøder, Tehler, D., Krogh, Nicolai, Nielsen, Henrik, Kraushar, M. L., Kirkeby, Agnete & Lund, Anders H., 2023, In: Developmental Cell. 58, 17, p. 1593-1609.e9Research output: Contribution to journal › Journal article › Research › peer-review
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MSLibrarian: Optimized Predicted Spectral Libraries for Data-Independent Acquisition Proteomics
Isaksson, M., Karlsson, C., Laurell, T., Kirkeby, Agnete & Heusel, M., 2022, In: Journal of Proteome Research. 21, 2, p. 535–546 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Comprehensive analysis of microrna expression in regionalized human neural progenitor cells reveals microRNA-10 as a caudalizing factor
Jönsson, M. E., Wahlestedt, J. N., Åkerblom, M., Kirkeby, Agnete, Malmevik, J., Brattaas, P. L., Jakobsson, J. & Parmar, M., 23 Sep 2015, In: Development (Cambridge). 142, 18, p. 3166-3177 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Single-Cell Analysis Reveals a Close Relationship between Differentiating Dopamine and Subthalamic Nucleus Neuronal Lineages.
Kee, N., Volakakis, N., Kirkeby, Agnete, Dahl, L., Storvall, H., Nolbrant, S., Lahti, L., Bjoerklund, A. K., Gillberg, L., Joodmardi, E., Sandberg, R., Parmar, M. & Perlmann, T., 5 Jan 2017, In: Cell Stem Cell. 20, 1, p. 29-40 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Preclinical assessment of a pluripotent cell therapy for treatment of Parkinson's Disease
Kirkeby, Agnete, 2021, In: Toxicology Letters. 350, Supplement, p. S37 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Building authentic midbrain dopaminergic neurons from stem CEllS - Lessons from development
Kirkeby, Agnete & Parmar, M., 1 Dec 2012, In: Translational Neuroscience. 3, 4, p. 314-319 6 p.Research output: Contribution to journal › Review › Research › peer-review
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Parkinson disease and growth factors — is GDNF good enough?
Kirkeby, Agnete & Barker, R. A., 1 Jun 2019, In: Nature Reviews Neurology. 15, 6, p. 312-314 3 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Functional and immunochemical characterisation of different antibodies against the erythropoietin receptor
Kirkeby, Agnete, van Beek, J., Nielsen, J., Leist, M. & Helboe, L., 15 Aug 2007, In: Journal of Neuroscience Methods. 164, 1, p. 50-58 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Generation of Regionally Specified Neural Progenitors and Functional Neurons from Human Embryonic Stem Cells under Defined Conditions
Kirkeby, Agnete, Grealish, S., Wolf, D. A., Nelander, J., Wood, J., Lundblad, M., Lindvall, O. & Parmar, M., 28 Jun 2012, In: Cell Reports. 1, 6, p. 703-714 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Predictive Markers Guide Differentiation to Improve Graft Outcome in Clinical Translation of hESC-Based Therapy for Parkinson's Disease.
Kirkeby, Agnete, Nolbrant, S., Tiklova, K., Heuer, A., Kee, N., Cardoso, T., Ottosson, D. R., Lelos, M. J., Rifes, P., Dunnett, S. B., Grealish, S., Perlmann, T. & Parmar, M., 2017, In: Cell Stem Cell. 20, 1, p. 135-148 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The stem cell niche finds its true north
Kirkeby, Agnete, Perlmann, T. & Pereira, C. F., 15 Aug 2016, In: Development (Cambridge). 143, 16, p. 2877-2881 5 p.Research output: Contribution to journal › Review › Research › peer-review
Strategies for bringing stem cell-derived dopamine neurons to the clinic: A European approach (STEM-PD)
Kirkeby, Agnete, Parmar, M. & Barker, R. A., 2017, Functional Neural Transplantation IV: Translation to Clinical Application, Part A. Vol. 230. p. 165-190 26 p. (Progress in Brain Research).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Generating regionalized neuronal cells from pluripotency, a step-by-stepprotocol
Kirkeby, Agnete, Nelander, J. & Parmar, M., 3 Jan 2013, In: Frontiers in Cellular Neuroscience. JANUARY 2013Research output: Contribution to journal › Journal article › Research › peer-review
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High-dose erythropoietin alters platelet reactivity and bleeding time in rodents in contrast to the neuroprotective variant carbamyl-erythropoietin (CEPO).
Kirkeby, Agnete, Torup, L., Bochsen, L., Kjalke, M., Abel, K., Theilgaard-Mønch, Kim, Johansson, P. I., Bjørn, S. E., Gerwien, J. & Leist, M., 2008, In: Thrombosis and Haemostasis. 99, 4, p. 720-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preclinical quality, safety, and efficacy of a human embryonic stem cell-derived product for the treatment of Parkinson's disease, STEM-PD
Parmar, M., Novo Nordisk Cell Therapy R&D, N. N. C. T. R. & Christiansen, Josefine Rågård, 2023, In: Cell Stem Cell. 30, 10, p. 1299-1314.e9 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 172979835
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IAP-Based Cell Sorting Results in Homogeneous Transplantable Dopaminergic Precursor Cells Derived from Human Pluripotent Stem Cells.
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
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Bringing Advanced Therapies for Parkinson's Disease to the Clinic: The Scientist's Perspective
Research output: Contribution to journal › Review › Research › peer-review
Published -
39
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Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson’s disease
Research output: Contribution to journal › Journal article › Research › peer-review
Published