Agnete Kirkeby
Guest Researcher, Associate professor, group leader, Associate Professor
Developmental Neuroscience
Blegdamsvej 3B
2200 København N
Kirkeby Lab
Blegdamsvej 3
2200 København N
Member of:
- 2024
- Published
Clinical translation of pluripotent stem cell-based therapies: successes and challenges
Christiansen, Josefine Rågård & Kirkeby, Agnete, 1 Apr 2024, In: Development (Cambridge, England). 151, 7Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Good Manufacturing Practice–compliant human induced pluripotent stem cells: from bench to putative clinical products
Novoa, J. J., Westra, I. M., Steeneveld, E., Fonseca Neves, N., Arendzen, C. H., Rajaei, B., Grundeken, E., Yildiz, M., van der Valk, W., Salvador, A., Carlotti, F., Dijkers, P. F., Locher, H., van den Berg, C. W., Raymond, K. I., Kirkeby, A., Mummery, C. L., Rabelink, T. J., Freund, C., Meij, P. & 1 others, , 2024, (E-pub ahead of print) In: Cytotherapy.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Characterising the RNA-binding protein atlas of the mammalian brain uncovers RBM5 misregulation in mouse models of Huntington's disease
Mullari, M., Fossat, Nicolas Julien, Skotte, Niels Henning, Asenjo-Martinez, A., Humphreys, D. T., Bukh, Jens, Kirkeby, Agnete, Scheel, Troels Kasper Høyer & Nielsen, Michael Lund, 2023, In: Nature Communications. 14, 20 p., 4348.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identifying secreted biomarkers of dopaminergic ventral midbrain progenitor cells
Rifes, P., Isaksson, M., Rusimbi, Charlotte Nuru, Ramón Santonja, A., Nelander, J., Laurell, T. & Kirkeby, Agnete, 2023, In: Stem Cell Research and Therapy. 14, 1, 354.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preclinical quality, safety, and efficacy of a human embryonic stem cell-derived product for the treatment of Parkinson's disease, STEM-PD
Parmar, M., Novo Nordisk Cell Therapy R&D, N. N. C. T. R. & Christiansen, Josefine Rågård, 2023, In: Cell Stem Cell. 30, 10, p. 1299-1314.e9 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ribosomal RNA 2′-O-methylation dynamics impact cell fate decisions
Häfner, Sophia Julia, Jansson, Martin David, Altinel, Kübra, Andersen, Kasper Langebjerg, Abay-Nørgaard, Zehra Caldwell, Ménard, Patrice, Fontenas, M., Sørensen, Daniel Madriz, Gay, David Michael, Arendrup, Frederic Schrøder, Tehler, D., Krogh, Nicolai, Nielsen, Henrik, Kraushar, M. L., Kirkeby, Agnete & Lund, Anders H., 2023, In: Developmental Cell. 58, 17, p. 1593-1609.e9Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Single-cell transcriptomics of human traumatic brain injury reveals activation of endogenous retroviruses in oligodendroglia
Garza, R., Sharma, Y., Atacho, D. A. M., Thiruvalluvan, Arun, Abu Hamdeh, S., Jönsson, M. E., Horvath, V., Adami, A., Ingelsson, M., Jern, P., Hammell, M. G., Englund, E., Kirkeby, Agnete, Jakobsson, J. & Marklund, N., 2023, In: Cell Reports. 42, 11, 19 p., 113395.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Current advancements of modelling schizophrenia using patient-derived induced pluripotent stem cells
Dubonyte, Ugne, Asenjo-Martinez, A., Werge, Thomas, Lage, K. & Kirkeby, Agnete, 2022, In: Acta Neuropathologica Communications. 10, 1, 20 p., 183.Research output: Contribution to journal › Review › Research › peer-review
- Published
Human Embryonic Stem Cell-Derived Dopaminergic Grafts Alleviate L-DOPA Induced Dyskinesia
Elabi, O. F., Pass, R., Sormonta, I., Nolbrant, S., Drummond, N., Kirkeby, Agnete, Kunath, T., Parmar, M. & Lane, E. L., 2022, In: Journal of Parkinson's Disease. 12, 6, p. 1881-1896 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MSLibrarian: Optimized Predicted Spectral Libraries for Data-Independent Acquisition Proteomics
Isaksson, M., Karlsson, C., Laurell, T., Kirkeby, Agnete & Heusel, M., 2022, In: Journal of Proteome Research. 21, 2, p. 535–546 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Bringing Advanced Therapies for Parkinson's Disease to the Clinic: The Scientist's Perspective
Tomishima, M. & Kirkeby, Agnete, 2021, In: Journal of Parkinson's Disease. 11, p. S135-S140 6 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Preclinical assessment of a pluripotent cell therapy for treatment of Parkinson's Disease
Kirkeby, Agnete, 2021, In: Toxicology Letters. 350, Supplement, p. S37 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- 2020
- Published
Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson’s disease
Tiklová, K., Nolbrant, S., Fiorenzano, A., Björklund, Å. K., Sharma, Y., Heuer, A., Gillberg, L., Hoban, D. B., Cardoso, T., Adler, A. F., Birtele, M., Lundén-Miguel, H., Volakakis, N., Kirkeby, Agnete, Perlmann, T. & Parmar, M., 1 Dec 2020, In: Nature Communications. 11, 1, 11 p., 2434.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic modification increases the survival and the neuroregenerative properties of transplanted neural stem cells
Korshunova, Irina, Rhein, S., vsz834, vsz834, Stölting, I., Pfisterer, U., Barta, A., Dmytriyeva, O., Kirkeby, Agnete, Schwaninger, M. & Khodosevich, Konstantin, 2020, In: JCI insight. 5, 4, p. 1-19 e126268.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modeling neural tube development by differentiation of human embryonic stem cells in a microfluidic WNT gradient
Rifes, P., Isaksson, M., Rathore, Gaurav Singh, Aldrin-Kirk, P., Moller, O. K., Barzaghi, G., Lee, J., Egerod, Kristoffer Lihme, Belmont-Rausch, Dylan Matthew, Parmar, M., Pers, Tune H, Laurell, T. & Kirkeby, Agnete, 2020, In: Nature Biotechnology. 38, p. 1265-1273 9 p.Research output: Contribution to journal › Letter › Research › peer-review
- 2019
- Published
Parkinson disease and growth factors — is GDNF good enough?
Kirkeby, Agnete & Barker, R. A., 1 Jun 2019, In: Nature Reviews Neurology. 15, 6, p. 312-314 3 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- 2018
- Published
Report of the international conference on manufacturing and testing of pluripotent stem cells
Abbot, S., Agbanyo, F., Ahlfors, J-E., Baghbaderani, B. A., Bartido, S., Bharti, K., Burke, C., Carlsson, B., Cavagnaro, J., Creasey, A., Lin, S., DiGiusto, D., Francissen, K., Gaffney, A., Goldring, C., Gorba, T., Griffiths, E., Lubiniecki, A., Vandeputte, J., Hanatani, T. & 23 others, , Nov 2018, In: Biologicals. 63, p. 67-83Research output: Contribution to journal › Conference article › Research › peer-review
- Published
Target-specific forebrain projections and appropriate synaptic inputs of hESC-derived dopamine neurons grafted to the midbrain of parkinsonian rats
Cardoso, T., Adler, A. F., Mattsson, B., Hoban, D. B., Nolbrant, S., Wahlestedt, J. N., Kirkeby, Agnete, Grealish, S., Björklund, A. & Parmar, M., 1 Sep 2018, In: The Journal of Comparative Neurology. 526, 13, p. 2133-2146Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A symphony of stem cells in Vienna - looking to the future
Porrello, E. R. & Kirkeby, Agnete, 8 Jun 2018, In: Development (Cambridge, England). 145, 11, 6 p., 163501.Research output: Contribution to journal › Conference article › Research › peer-review
- Published
Sense-Antisense lncRNA Pair Encoded by Locus 6p22.3 Determines Neuroblastoma Susceptibility via the USP36-CHD7-SOX9 Regulatory Axis
Mondal, T., Juvvuna, P. K., Kirkeby, A., Mitra, S., Kosalai, S. T., Traxler, L., Hertwig, F., Wernig-Zorc, S., Miranda, C., Deland, L., Volland, R., Bartenhagen, C., Bartsch, D., Bandaru, S., Engesser, A., Subhash, S., Martinsson, T., Carén, H., Akyürek, L. M., Kurian, L. & 5 others, , 12 Mar 2018, In: Cancer Cell. 33, 3, p. 417-434.e7Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
IAP-Based Cell Sorting Results in Homogeneous Transplantable Dopaminergic Precursor Cells Derived from Human Pluripotent Stem Cells.
Lehnen, D., Barral, S., Cardoso, T., Grealish, S., Heuer, A., Smiyakin, A., Kirkeby, Agnete, Kollet, J., Cremer, H., Parmar, M., Bosio, A. & Knoebel, S., Oct 2017, In: Stem Cell Reports. 9, 4, p. 1207-1220 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
Term amniotic fluid: an unexploited reserve of mesenchymal stromal cells for reprogramming and potential cell therapy applications.
Moraghebi, R., Kirkeby, Agnete, Chaves, P., Roenn, R. E., Sitnicka, E., Parmar, M., Larsson, M., Herbst, A. & Woods, N., 25 Aug 2017, In: Stem Cell Research & Therapy. 8, 12 p., 190.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Single-Cell Analysis Reveals a Close Relationship between Differentiating Dopamine and Subthalamic Nucleus Neuronal Lineages.
Kee, N., Volakakis, N., Kirkeby, Agnete, Dahl, L., Storvall, H., Nolbrant, S., Lahti, L., Bjoerklund, A. K., Gillberg, L., Joodmardi, E., Sandberg, R., Parmar, M. & Perlmann, T., 5 Jan 2017, In: Cell Stem Cell. 20, 1, p. 29-40 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anatomical and Molecular insight into the developing entorhinal cortex in a large mammalian species, the pig.
Liu, Y., Peralvo Vidal, Juan Miguel, Thomsen, Preben Dybdahl, Møllgård, Kjeld, Kirkeby, Agnete & Hall, Vanessa Jane, 2017.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
Generation of high-purity human ventral midbrain dopaminergic progenitors for in vitro maturation and intracerebral transplantation
Nolbrant, S., Heuer, A., Parmar, M. & Kirkeby, Agnete, 2017, In: Nature Protocols. 12, 9, p. 1962-1979Research output: Contribution to journal › Journal article › Research › peer-review
ID: 172979835
Most downloads
-
128
downloads
IAP-Based Cell Sorting Results in Homogeneous Transplantable Dopaminergic Precursor Cells Derived from Human Pluripotent Stem Cells.
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
42
downloads
Bringing Advanced Therapies for Parkinson's Disease to the Clinic: The Scientist's Perspective
Research output: Contribution to journal › Review › Research › peer-review
Published -
39
downloads
Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson’s disease
Research output: Contribution to journal › Journal article › Research › peer-review
Published