Agnete Kirkeby

Agnete Kirkeby

Guest Researcher, Associate professor, group leader


  1. 2023
  2. Published

    Characterising the RNA-binding protein atlas of the mammalian brain uncovers RBM5 misregulation in mouse models of Huntington's disease

    Mullari, M., Fossat, Nicolas Julien, Skotte, Niels Henning, Asenjo-Martinez, A., Humphreys, D. T., Bukh, Jens, Kirkeby, Agnete, Scheel, Troels Kasper Høyer & Nielsen, Michael Lund, 2023, In: Nature Communications. 14, 20 p., 4348.

    Research output: Contribution to journalJournal articlepeer-review

  3. Published

    Identifying secreted biomarkers of dopaminergic ventral midbrain progenitor cells

    Rifes, P., Isaksson, M., Rusimbi, Charlotte Nuru, Ramón Santonja, A., Nelander, J., Laurell, T. & Kirkeby, Agnete, 2023, In: Stem Cell Research and Therapy. 14, 1, 354.

    Research output: Contribution to journalJournal articlepeer-review

  4. Published

    Preclinical quality, safety, and efficacy of a human embryonic stem cell-derived product for the treatment of Parkinson's disease, STEM-PD

    Novo Nordisk Cell Therapy R&D, N. N. C. T. R., 2023, In: Cell Stem Cell. 30, 10, p. 1299-1314.e9 17 p.

    Research output: Contribution to journalJournal articlepeer-review

  5. Published
  6. Published

    Single-cell transcriptomics of human traumatic brain injury reveals activation of endogenous retroviruses in oligodendroglia

    Garza, R., Sharma, Y., Atacho, D. A. M., Thiruvalluvan, Arun, Abu Hamdeh, S., Jönsson, M. E., Horvath, V., Adami, A., Ingelsson, M., Jern, P., Hammell, M. G., Englund, E., Kirkeby, Agnete, Jakobsson, J. & Marklund, N., 2023, In: Cell Reports. 42, 11, 19 p., 113395.

    Research output: Contribution to journalJournal articlepeer-review

  7. 2022
  8. Published

    Current advancements of modelling schizophrenia using patient-derived induced pluripotent stem cells

    Dubonyte, Ugne, Asenjo-Martinez, A., Werge, Thomas, Lage, K. & Kirkeby, Agnete, 2022, In: Acta Neuropathologica Communications. 10, 1, 20 p., 183.

    Research output: Contribution to journalReviewpeer-review

  9. Published

    Human Embryonic Stem Cell-Derived Dopaminergic Grafts Alleviate L-DOPA Induced Dyskinesia

    Elabi, O. F., Pass, R., Sormonta, I., Nolbrant, S., Drummond, N., Kirkeby, Agnete, Kunath, T., Parmar, M. & Lane, E. L., 2022, In: Journal of Parkinson's Disease. 12, 6, p. 1881-1896 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  10. Published

    MSLibrarian: Optimized Predicted Spectral Libraries for Data-Independent Acquisition Proteomics

    Isaksson, M., Karlsson, C., Laurell, T., Kirkeby, Agnete & Heusel, M., 2022, In: Journal of Proteome Research. 21, 2, p. 535–546 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  11. 2021
  12. Published

    Bringing Advanced Therapies for Parkinson's Disease to the Clinic: The Scientist's Perspective

    Tomishima, M. & Kirkeby, Agnete, 2021, In: Journal of Parkinson's Disease. 11, p. S135-S140 6 p.

    Research output: Contribution to journalReviewpeer-review

  13. Published

    Preclinical assessment of a pluripotent cell therapy for treatment of Parkinson's Disease

    Kirkeby, Agnete, 2021, In: Toxicology Letters. 350, Supplement, p. S37 1 p.

    Research output: Contribution to journalConference abstract in journalpeer-review

  14. 2020
  15. Published

    Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson’s disease

    Tiklová, K., Nolbrant, S., Fiorenzano, A., Björklund, Å. K., Sharma, Y., Heuer, A., Gillberg, L., Hoban, D. B., Cardoso, T., Adler, A. F., Birtele, M., Lundén-Miguel, H., Volakakis, N., Kirkeby, Agnete, Perlmann, T. & Parmar, M., 1 Dec 2020, In: Nature Communications. 11, 1, 11 p., 2434.

    Research output: Contribution to journalJournal articlepeer-review

  16. Published

    Genetic modification increases the survival and the neuroregenerative properties of transplanted neural stem cells

    Korshunova, Irina, Rhein, S., vsz834, vsz834, Stölting, I., Pfisterer, U., Barta, A., Dmytriyeva, O., Kirkeby, Agnete, Schwaninger, M. & Khodosevich, Konstantin, 2020, In: JCI insight. 5, 4, p. 1-19 e126268.

    Research output: Contribution to journalJournal articlepeer-review

  17. Published

    Modeling neural tube development by differentiation of human embryonic stem cells in a microfluidic WNT gradient

    Rifes, P., Isaksson, M., Rathore, Gaurav Singh, Aldrin-Kirk, P., Moller, O. K., Barzaghi, G., Lee, J., Egerod, Kristoffer Lihme, Belmont-Rausch, Dylan Matthew, Parmar, M., Pers, Tune H, Laurell, T. & Kirkeby, Agnete, 2020, In: Nature Biotechnology. 38, p. 1265-1273 9 p.

    Research output: Contribution to journalLetterpeer-review

  18. 2019
  19. Published

    Parkinson disease and growth factors — is GDNF good enough?

    Kirkeby, Agnete & Barker, R. A., 1 Jun 2019, In: Nature Reviews Neurology. 15, 6, p. 312-314 3 p.

    Research output: Contribution to journalComment/debatepeer-review

  20. 2018
  21. Published

    Report of the international conference on manufacturing and testing of pluripotent stem cells

    Abbot, S., Agbanyo, F., Ahlfors, J-E., Baghbaderani, B. A., Bartido, S., Bharti, K., Burke, C., Carlsson, B., Cavagnaro, J., Creasey, A., Lin, S., DiGiusto, D., Francissen, K., Gaffney, A., Goldring, C., Gorba, T., Griffiths, E., Lubiniecki, A., Vandeputte, J., Hanatani, T. & 23 others, Hayakawa, T., Heki, T., Hoogendoorn, K., Kawamata, S., Kimura, H., Kirkeby, Agnete, Knezevic, I., Lebkowski, J., Lin-Gibson, S., O'Shea, O., Pera, M., Petricciani, J., Pigeau, G., Ratcliffe, A., Sato, Y., Schumann, G. G., Shingleton, W., Stacey, C. G., Sullivan, S., Svendsen, C. N., Trouvin, J., Yuan, B. & Zoon, K., Nov 2018, In: Biologicals. 63, p. 67-83

    Research output: Contribution to journalConference articlepeer-review

  22. Published

    Target-specific forebrain projections and appropriate synaptic inputs of hESC-derived dopamine neurons grafted to the midbrain of parkinsonian rats

    Cardoso, T., Adler, A. F., Mattsson, B., Hoban, D. B., Nolbrant, S., Wahlestedt, J. N., Kirkeby, Agnete, Grealish, S., Björklund, A. & Parmar, M., 1 Sep 2018, In: The Journal of Comparative Neurology. 526, 13, p. 2133-2146

    Research output: Contribution to journalJournal articlepeer-review

  23. Published

    A symphony of stem cells in Vienna - looking to the future

    Porrello, E. R. & Kirkeby, Agnete, 8 Jun 2018, In: Development (Cambridge, England). 145, 11, 6 p., 163501.

    Research output: Contribution to journalConference articlepeer-review

  24. Published

    Sense-Antisense lncRNA Pair Encoded by Locus 6p22.3 Determines Neuroblastoma Susceptibility via the USP36-CHD7-SOX9 Regulatory Axis

    Mondal, T., Juvvuna, P. K., Kirkeby, A., Mitra, S., Kosalai, S. T., Traxler, L., Hertwig, F., Wernig-Zorc, S., Miranda, C., Deland, L., Volland, R., Bartenhagen, C., Bartsch, D., Bandaru, S., Engesser, A., Subhash, S., Martinsson, T., Carén, H., Akyürek, L. M., Kurian, L. & 5 others, Kanduri, M., Huarte, M., Kogner, P., Fischer, M. & Kanduri, C., 12 Mar 2018, In: Cancer Cell. 33, 3, p. 417-434.e7

    Research output: Contribution to journalJournal articlepeer-review

  25. 2017
  26. Published

    IAP-Based Cell Sorting Results in Homogeneous Transplantable Dopaminergic Precursor Cells Derived from Human Pluripotent Stem Cells.

    Lehnen, D., Barral, S., Cardoso, T., Grealish, S., Heuer, A., Smiyakin, A., Kirkeby, Agnete, Kollet, J., Cremer, H., Parmar, M., Bosio, A. & Knoebel, S., Oct 2017, In: Stem Cell Reports. 9, 4, p. 1207-1220 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  27. Term amniotic fluid: an unexploited reserve of mesenchymal stromal cells for reprogramming and potential cell therapy applications.

    Moraghebi, R., Kirkeby, Agnete, Chaves, P., Roenn, R. E., Sitnicka, E., Parmar, M., Larsson, M., Herbst, A. & Woods, N., 25 Aug 2017, In: Stem Cell Research & Therapy. 8, 12 p., 190.

    Research output: Contribution to journalJournal articlepeer-review

  28. Published

    Single-Cell Analysis Reveals a Close Relationship between Differentiating Dopamine and Subthalamic Nucleus Neuronal Lineages.

    Kee, N., Volakakis, N., Kirkeby, Agnete, Dahl, L., Storvall, H., Nolbrant, S., Lahti, L., Bjoerklund, A. K., Gillberg, L., Joodmardi, E., Sandberg, R., Parmar, M. & Perlmann, T., 5 Jan 2017, In: Cell Stem Cell. 20, 1, p. 29-40 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  29. Published
  30. Published

    Generation of high-purity human ventral midbrain dopaminergic progenitors for in vitro maturation and intracerebral transplantation

    Nolbrant, S., Heuer, A., Parmar, M. & Kirkeby, Agnete, 2017, In: Nature Protocols. 12, 9, p. 1962-1979

    Research output: Contribution to journalJournal articlepeer-review

  31. Predictive Markers Guide Differentiation to Improve Graft Outcome in Clinical Translation of hESC-Based Therapy for Parkinson's Disease.

    Kirkeby, Agnete, Nolbrant, S., Tiklova, K., Heuer, A., Kee, N., Cardoso, T., Ottosson, D. R., Lelos, M. J., Rifes, P., Dunnett, S. B., Grealish, S., Perlmann, T. & Parmar, M., 2017, In: Cell Stem Cell. 20, 1, p. 135-148 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  32. Strategies for bringing stem cell-derived dopamine neurons to the clinic: A European approach (STEM-PD)

    Kirkeby, Agnete, Parmar, M. & Barker, R. A., 2017, Functional Neural Transplantation IV: Translation to Clinical Application, Part A. Vol. 230. p. 165-190 26 p. (Progress in Brain Research).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

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